验证数据展示
产品信息
68137-1-PBS targets TSPO in WB, IF/ICC, ELISA applications and shows reactivity with rat, mouse, human samples.
经测试应用 | WB, IF/ICC, ELISA Application Description |
经测试反应性 | rat, mouse, human |
免疫原 | TSPO fusion protein Ag7475 种属同源性预测 |
宿主/亚型 | Mouse / IgM |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | translocator protein (18kDa) |
别名 | Peripheral-type benzodiazepine receptor, MBR, BZRP, 1D1F12 |
计算分子量 | 18 kDa |
观测分子量 | 18 kDa |
GenBank蛋白编号 | BC001110 |
基因名称 | TSPO |
Gene ID (NCBI) | 706 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | P30536 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
TSPO encodes the translocator protein, belonging to tryptophan-rich sensory protein family. The protein is mainly localized in the outer mitochondrial membrane and expressed in steroid-synthesizing tissues (PMID:32881658, PMID:1326278). TSPO is involved in the translocation of cholesterol from the outer to inner mitochondrial membrane (PMID:21119734). In response to injury, TSPO has a upregulated expression in the peripheral nervous system (PMID:32423330, PMID:23251719). TSPO is also as a biomarker in a non-invasive procedure including detecting the inflammation in the heart and atherosclerotic plaques (PMID:24402571).