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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 68137-1-Ig (same clone as 68137-1-PBS)

    WB analysis using 68137-1-Ig (same clone as 68137-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 68137-1-Ig (TSPO/PBR antibody) at dilution of 1:8000 incubated at room temperature for 1.5 hours. The membrane was stripped and reblotted with HRP-conjugated GAPDH Monoclonal antibody (HRP-60004) as loading control. This data was developed using the same antibody clone with 68137-1-PBS in a different storage buffer formulation.

  • WB analysis using 68137-1-Ig (same clone as 68137-1-PBS)

    WB analysis using 68137-1-Ig (same clone as 68137-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 68137-1-Ig (TSPO/PBR antibody) at dilution of 1:8000 incubated at room temperature for 1.5 hours. The membrane was stripped and reblotted with HRP-conjugated GAPDH Monoclonal antibody (HRP-60004) as loading control. This data was developed using the same antibody clone with 68137-1-PBS in a different storage buffer formulation.

  • WB analysis of Jurkat using 68137-1-Ig (same clone as 68137-1-PBS)

    WB analysis of Jurkat using 68137-1-Ig (same clone as 68137-1-PBS)

    Jurkat cells were subjected to SDS PAGE followed by western blot with 68137-1-Ig (TSPO/PBR antibody) at dilution of 1:8000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68137-1-PBS in a different storage buffer formulation.

  • IF Staining of NIH/3T3 using 68137-1-Ig (same clone as 68137-1-PBS)

    IF Staining of NIH/3T3 using 68137-1-Ig (same clone as 68137-1-PBS)

    Immunofluorescent analysis of (-20°C Ethanol) fixed NIH/3T3 cells using TSPO/PBR antibody (68137-1-Ig, Clone: 1D1F12 ) at dilution of 1:800 and CoraLite®488-Conjugated AffiniPure Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 68137-1-PBS in a different storage buffer formulation.

TSPO Monoclonal antibody, PBS Only

TSPO Monoclonal Antibody for WB, IF/ICC, ELISA
Cat No. 68137-1-PBS

产品说明书

CloneNo. 1D1F12

宿主/亚型

Mouse / IgM

种属反应性

human, mouse, rat

应用

WB, IF/ICC, ELISA

别名

TSPO/PBR, 1D1F12, BZRP, MBR, Peripheral-type benzodiazepine receptor

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

68137-1-PBS targets TSPO in WB, IF/ICC, ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IF/ICC, ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 TSPO fusion protein Ag7475 种属同源性预测
宿主/亚型 Mouse / IgM
抗体类别 Monoclonal
产品类型 Antibody
全称 translocator protein (18kDa)
别名 TSPO/PBR, 1D1F12, BZRP, MBR, Peripheral-type benzodiazepine receptor
计算分子量 18 kDa
观测分子量18 kDa
GenBank蛋白编号BC001110
基因名称 TSPO
Gene ID (NCBI) 706
偶联类型 Unconjugated
形式 Liquid
纯化方式Caprylic acid/ammonium sulfate precipitation
UNIPROT IDP30536
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

TSPO encodes the translocator protein, belonging to tryptophan-rich sensory protein family. The protein is mainly localized in the outer mitochondrial membrane and expressed in steroid-synthesizing tissues (PMID:32881658, PMID:1326278). TSPO is involved in the translocation of cholesterol from the outer to inner mitochondrial membrane (PMID:21119734). In response to injury, TSPO has a upregulated expression in the peripheral nervous system (PMID:32423330, PMID:23251719). TSPO is also as a biomarker in a non-invasive procedure including detecting the inflammation in the heart and atherosclerotic plaques (PMID:24402571).