Tie2 Polyclonal antibody

Tie2 Polyclonal Antibody for ELISA
Cat No. 13282-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

ELISA

Angiopoietin 1 receptor, CD202B, hTIE2, p140 TEK, TEK, TIE 2, TIE2, VMCM, VMCM1

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
规格: 

-/ -


产品信息

13282-1-AP targets Tie2 in ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 Tie2 fusion protein Ag4032 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 TEK tyrosine kinase, endothelial
别名 Angiopoietin 1 receptor, CD202B, hTIE2, p140 TEK, TEK, TIE 2, TIE2, VMCM, VMCM1
计算分子量 1124 aa, 126 kDa
GenBank蛋白编号BC035514
基因名称 Tie2
Gene ID (NCBI) 7010
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ02763
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Tie2 (also known as TEK) is a tyrosine-protein kinase expressed almost exclusively on endothelial cells. It contains two immunoglobulin-like domains, three epidermal growth factor (EGF)-like domains and three fibronectin type III repeats. Tie2 acts as cell-surface receptor for ANGPT1, ANGPT2 and ANGPT4 and regulates angiogenesis, endothelial cell survival, proliferation, migration, adhesion and cell spreading, reorganization of the actin cytoskeleton, but also maintenance of vascular quiescence. Mutations in the gene of Tie2 are associated with inherited venous malformations of the skin and mucous membranes.

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