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Species Reactivity
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验证数据展示

  • WB analysis of mouse colon using 21159-1-AP (same clone as 21159-1-PBS)

    WB analysis of mouse colon using 21159-1-AP (same clone as 21159-1-PBS)

    mouse colon tissue were subjected to SDS PAGE followed by western blot with 21159-1-AP (TEAD2 Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 21159-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO验证

TEAD2 Polyclonal antibody, PBS Only

TEAD2 Polyclonal Antibody for WB, Indirect ELISA
Cat No. 21159-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, Indirect ELISA

别名

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

21159-1-PBS targets TEAD2 in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原

CatNo: Ag14074

Product name: Recombinant human TEAD2 protein

Source: e coli.-derived, PET28a

Tag: 6*His

Domain: 121-251 aa of BC051301

Sequence: DQVSKDKAFQTMATMSSAQLISAPSLQAKLGPTGPQVVQASELFQFWSGGSGPPWNVPDVKPFSQTPFTLSLTPPSTDLPGYEPPQALSPLPPPTPSPPAWQARGLGTARLQLVEFSAFVEPPDAVDSYQR

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 TEA domain family member 2
别名
计算分子量 447 aa, 49 kDa
观测分子量 55-65 kDa
GenBank蛋白编号BC051301
基因名称 TEAD2
Gene ID (NCBI) 8463
RRIDAB_2861186
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ15562
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

TEAD2 belongs to a protein family that shares the TEA/ATTS domain. It acts as a transcriptional factor by cooperatively binding to the GT-IIC and Sph(I 1 II) enhansons in the simian virus 40 (SV40) enhancer. Also, it can modulate SV40 late transcription together with a large T antigen. The transcriptional activity of TEAD2 required several regions of the proteins, TBP-associated factors, and limiting transcriptional intermediary factors. TEAD2 also performs an essential role in the Hippo signaling pathway. TEAD2 regulates gene expression of YAP1 and WWTR1/TAZ, thus mediating cell proliferation, migration, and epithelial-mesenchymal transition induction. TEAD2 is strongly expressed in the human ovarian carcinoma cell line.