• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 21496-1-AP

    WB analysis using 21496-1-AP

    Various lysates were subjected to SDS PAGE followed by western blot with 21496-1-AP (SLITRK5 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours.

  • IF Staining of A431 using 21496-1-AP

    IF Staining of A431 using 21496-1-AP

    Immunofluorescent analysis of (4% PFA) fixed A431 cells using SLITRK5 antibody (21496-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L), CL594-phalloidin (red).

SLITRK5 Polyclonal antibody

SLITRK5 Polyclonal Antibody for WB, IF/ICC, ELISA
Cat No. 21496-1-AP

产品说明书

引用文献(1)

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, IF/ICC, ELISA

别名

SLIT and NTRK like protein 5, LRRC11, Leucine-rich repeat-containing protein 11, KIAA0918, FLJ58374

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -

点击咨询售前客服

点击咨询售后客服

经过测试的应用

Positive WB detected inHEK-293 cells
Positive IF/ICC detected inA431 cells

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:500-1:3000
Immunofluorescence (IF)/ICCIF/ICC : 1:200-1:800
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

发表文章中的应用

WBSee 1 publications below

产品信息

21496-1-AP targets SLITRK5 in WB, IF/ICC, ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, IF/ICC, ELISA Application Description
文献引用应用WB
经测试反应性 human, mouse
文献引用反应性mouse
免疫原 SLITRK5 fusion protein Ag15880 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 SLIT and NTRK-like family, member 5
别名 SLIT and NTRK like protein 5, LRRC11, Leucine-rich repeat-containing protein 11, KIAA0918, FLJ58374
计算分子量 958 aa, 107 kDa
观测分子量100-110 kDa
GenBank蛋白编号BC098106
基因名称 SLITRK5
Gene ID (NCBI) 26050
RRIDAB_3085658
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDO94991
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

SLITRK5 (NTRK-like protein-5), a neuron-specific transmembrane protein, acts as a negative regulator of hedgehog signaling in osteoblasts. SLITRK5 is selectively expressed in osteoblasts and loss of SLITRK5 enhanced osteoblast differentiation in vitro and in vivo. It is a therapeutic target to enhance bone formation (PMID: 34326333). SLITRK5 deficiency impairs corticostriatal circuitry and leads to obsessive-compulsive-like behaviors in mice (PMID: 20418887).

实验方案

Product Specific Protocols
WB protocol for SLITRK5 antibody 21496-1-APDownload protocol
IF protocol for SLITRK5 antibody 21496-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
mouseWB

EMBO Rep

Schizophrenia-related Xpo7 haploinsufficiency leads to behavioral and nuclear transport pathologies

Authors - Saori Toyoda
View Article