验证数据展示
产品信息
30861-1-PBS targets SGLT1 in WB, IHC, IF-P, IP, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
经测试应用 | WB, IHC, IF-P, IP, Indirect ELISA Application Description |
经测试反应性 | human, mouse, rat |
免疫原 | SGLT1 fusion protein Ag29338 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Polyclonal |
产品类型 | Antibody |
全称 | solute carrier family 5 (sodium/glucose cotransporter), member 1 |
别名 | SLC5A1, High affinity sodium-glucose cotransporter |
计算分子量 | 73 kDa |
观测分子量 | 73 kDa |
GenBank蛋白编号 | NM_000343 |
基因名称 | SGLT1 |
Gene ID (NCBI) | 6523 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Antigen affinity purification |
UNIPROT ID | P13866 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
SLC5A1, also known as SGLT1, is a sodium-dependent glucose transporter (SGLT) family member. SGLT1 couples sugar transport to Na+ gradients across the intestinal brush border (PMID: 8563765). SGLT1 mediates active glucose and galactose absorption in the intestine and renal glucose scavenging. Mutations in SGLT1 cause glucose-galactose malabsorption (GGM) syndrome (PMID: 34880492). SGLT1 is expressed in intestine and endometrial cells (PMID: 2490366, 28974690).