验证数据展示
产品信息
Rheumatoid factors are antibodies directed against the Fc region of immunoglobulin G.
| 经测试应用 | Application Description |
| 经测试反应性 | human |
| 免疫原 |
N/A 种属同源性预测 |
| 宿主/亚型 | Human / IgM |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | Rheumatoid Factor IgM |
| 别名 | RF-IgM, Rheumatoid Factor |
| 基因名称 | |
| Gene ID (NCBI) | |
| RRID | AB_3745150 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Affinity purification |
| 储存缓冲液 | 50mM HEPES, 150mM NaCl, 5mM EDTA, 0.1% CHAPS, 10% Sucrose and 0.1% Proclin300, pH 7.3. |
| 储存条件 | Store at 2-8°C. Stable for one year after shipment. |
背景介绍
Rheumatoid arthritis is an autoimmune disease in which the body's immune system attacks the joints. Rheumatoid factors are the autoantibodies identified in rheumatoid arthritis that target the Fc region of IgG. Among the different rheumatoid factor isotypes, rheumatoid factor IgM is the most clinically used to estimate disease prognosis in rheumatoid arthritis (PMID: 36341420).
