验证数据展示
Planning an IHC experiment? We recommend our IHCeasy® TBK1 Ready-To-Use IHC Kit. TBK1 primary antibody included.
发表文章中的应用
| WB | See 1 publications below |
产品信息
82382-2-PBS targets Phospho-TBK1 (Ser172) in WB, FC (Intra), Indirect ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, FC (Intra), Indirect ELISA Application Description |
| 文献引用应用 | WB |
| 经测试反应性 | human |
| 文献引用反应性 | mouse |
| 免疫原 |
Peptide 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | TANK-binding kinase 1 |
| 别名 | p TBK1 (Ser172), Phospho TBK1 (Ser172), Phospho-NAK (Ser172), Phospho-TBK1, Phospho-TBK1-Ser172 |
| 观测分子量 | 84 kDa |
| GenBank蛋白编号 | BC034950 |
| 基因名称 | TBK1 |
| Gene ID (NCBI) | 29110 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purfication |
| UNIPROT ID | Q9UHD2 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
The serine/threonine protein kinase TBK1, discovered two decades ago as a member of the IκB kinase (IKK) protein kinase family, plays crucial roles in regulating innate immune response by promoting type I interferon (IFN) and modulating NF-κB signaling. The phosphorylation of Ser172 residue on TBK1 is critical and is commonly used as an indicator for its activity. (PMID: 39279883)
