验证数据展示
产品信息
15481-1-PBS targets PEX11A in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | human, mouse |
| 免疫原 |
CatNo: Ag7797 Product name: Recombinant human PEX11A protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 1-247 aa of BC009697 Sequence: MDAFTRFTNQTQGRDRLFRATQYTCMLLRYLLEPKAGKEKVVMKLKKLESSVSTGRKWFRLGNVVHAIQATEQSIHATDLVPRLCLTLANLNRVIYFICDTILWVRSVGLTSGINKEKWRTRAAHHYYYSLLLSLVRDLYEISLQMKRVTCDRAKKEKSASQDPLWFSVAEEETEWLQSFLLLLFRSLKQHPPLLLDTVKNLCDILNPLDQLGIYKSNPGIIGLGGLVSSIAGMITVAYPQMKLKTR 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | peroxisomal biogenesis factor 11 alpha |
| 别名 | |
| 计算分子量 | 28 kDa |
| 观测分子量 | 28 kDa |
| GenBank蛋白编号 | BC009697 |
| 基因名称 | PEX11A |
| Gene ID (NCBI) | 8800 |
| RRID | AB_3085464 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | O75192 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Peroxisomes are ubiquitous organelles bound by a single membrane. Peroxisomal biogenesis factor 11 alpha (PEX11A) is one of PEX11 gene family members involved in peroxisome elongation. PEX11A is highly expressed in the kidney and liver (PMID: 25113963). PEX11A deficiency will impaire peroxisome elongation, leading to the reduction of functional peroxisome, eventually leading to the reduction of fatty acid oxidation capacity and the formation of steatosis (PMID: 23169785; PMID: 25113963)
