验证数据展示
产品信息
68284-1-PBS targets NEUROD2 in WB, Indirect ELISA applications and shows reactivity with Human, mouse, pig samples.
经测试应用 | WB, Indirect ELISA Application Description |
经测试反应性 | Human, mouse, pig |
免疫原 | NEUROD2 fusion protein Ag26068 种属同源性预测 |
宿主/亚型 | Mouse / IgG1 |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | neurogenic differentiation 2 |
别名 | bHLHa1, NDRF, NeuroD related factor, NEUROD2, neurogenic differentiation 2 |
计算分子量 | 41 kDa |
观测分子量 | 41-50 kDa |
GenBank蛋白编号 | BC022481 |
基因名称 | NEUROD2 |
Gene ID (NCBI) | 4761 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein G purification |
UNIPROT ID | Q15784 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
NEUROD2 (Neurogenic differentiation factor 2), is transcriptional regulator that regulates early neuronal differentiation during development (PMID: 7754368). NeuroD2 is expressed in the postnatal cortex and mediate the activity-dependent refinement of thalamocortical axon terminals (PMID: 17453014). NeuroD2 is mainly involved in the development of the cerebellar and hippocampal granular neurons, neurons in the basolateral nucleus of amygdala and the hypothalamic-pituitary axis. Mutantions in NEUROD2 can cause neurodevelopmental disorders including intellectual disability and autism spectrum disorders (PMID: 34188164).