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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 11410-1-AP (same clone as 11410-1-PBS)

    WB analysis using 11410-1-AP (same clone as 11410-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 11410-1-AP (NAT2 antibody) at dilution of 1:6000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11410-1-PBS in a different storage buffer formulation.

  • IHC staining of human small intestine using 11410-1-AP (same clone as 11410-1-PBS)

    IHC staining of human small intestine using 11410-1-AP (same clone as 11410-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human small intestine tissue slide using 11410-1-AP (NAT2 antibody) at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 11410-1-PBS in a different storage buffer formulation.

  • FC experiment of MCF-7 using 11410-1-AP (same clone as 11410-1-PBS)

    FC experiment of MCF-7 using 11410-1-AP (same clone as 11410-1-PBS)

    1x10^6 MCF-7 cells were intracellularly stained with 0.8 ug NAT2 Polyclonal antibody (11410-1-AP) and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L) (SA00013-2)(red), or 0.8 ug Rabbit IgG control Rabbit PolyAb (30000-0-AP) (blue). Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C). This data was developed using the same antibody clone with 11410-1-PBS in a different storage buffer formulation.

  • IHC staining of human breast cancer using 11410-1-AP (same clone as 11410-1-PBS)

    IHC staining of human breast cancer using 11410-1-AP (same clone as 11410-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 11410-1-AP (NAT2 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11410-1-PBS in a different storage buffer formulation.

  • IHC staining of human breast cancer using 11410-1-AP (same clone as 11410-1-PBS)

    IHC staining of human breast cancer using 11410-1-AP (same clone as 11410-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 11410-1-AP (NAT2 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11410-1-PBS in a different storage buffer formulation.

NAT2 Polyclonal antibody, PBS Only

NAT2 Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 11410-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, Indirect ELISA

别名

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

11410-1-PBS targets NAT2 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原

CatNo: Ag1953

Product name: Recombinant human NAT2 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1-290 aa of BC015878

Sequence: MDIEAYFERIGYKNSRNKLDLETLTDILEHQIRAVPFENLNMHCGQAMELGLEAIFDHIVRRNRGGWCLQVNQLLYWALTTIGFQTTMLGGYFYIPPVNKYSTGMVHLLLQVTIDGRNYIVDAGSGSSSQMWQPLELISGKDQPQVPCIFCLTEERGIWYLDQIRREQYITNKEFLNSHLLPKKKHQKIYLFTLEPQTIEDFESMNTYLQTSPTSSFITTSFCSLQTPEGVYCLVGFILTYRKFNYKDNTDLVEFKTLTEEEVEEVLKNIFKISLGRNLVPKPGDGSLTI

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 N-acetyltransferase 2 (arylamine N-acetyltransferase)
别名
计算分子量 33.5 kDa
观测分子量38 kDa
GenBank蛋白编号BC015878
基因名称 NAT2
Gene ID (NCBI) 10
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDP11245
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

NAT2 (Arylamine N-acetyltransferase 2) is well-known for its role in the phase II metabolism of xenobiotics and drugs (PMID:36156098). NAT2 and its isozyme, arylamine N-acetyltransferase 1 (NAT1), play key roles in the detoxification of carcinogenic arylamines and xenobiotics by catalyzing acetyl-coenzyme A (CoA)-dependent biotransformation of arylamines to N-arylacetamides. Endogenous NAT2 expression is limited to the liver and small and large intestines, suggesting that NAT2 plays organ-specific roles (PMID:24467436).