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验证数据展示

  • Single Cell Sequencing experiment G65169-1-5C on Resting PBMC

    Single Cell Sequencing experiment G65169-1-5C on Resting PBMC

    G65169-1-5C was used to stain Resting PBMC and analyzed with 10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing kit with Fix-Stain protocol.

  • Single Cell Sequencing experiment G65169-1-5C on PBMC treated with 4hr LPS + TI

    Single Cell Sequencing experiment G65169-1-5C on PBMC treated with 4hr LPS + TI

    G65169-1-5C was used to stain PBMC under 4hr LPS + TI treatment and analyzed with 10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing kit with Fix-Stain protocol.

MultiPro® 5CFLX Anti-Human CD163 (GHI/61)

CD163 Monoclonal Antibody for Single Cell (Intra)
Cat No. G65169-1-5C

产品说明书

CloneNo. GHI/61

宿主/亚型

Mouse / IgG1, kappa

种属反应性

Human

应用

Single Cell (Intra)

别名

CD163, CD163 molecule, Hemoglobin scavenger receptor, M130, MM130, sCD163

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  5CFLX
规格价格库存

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经过测试的应用

Positive Single Cell (Intra) detected in10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing product.
Planning an IHC experiment? We recommend our IHCeasy CD163 Ready-To-Use IHC Kit. CD163 primary antibody included.

推荐稀释比

应用推荐稀释比
SINGLE CELL (INTRA)<0.5ug/test
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

产品信息

G65169-1-5C targets CD163 in Single Cell (Intra) applications and shows reactivity with Human samples.

经测试应用 Single Cell (Intra) Application Description
经测试反应性 Human
免疫原

fusion protein

种属同源性预测
宿主/亚型 Mouse / IgG1, kappa
抗体类别 Oligo Conjugate
产品类型 Monoclonal
全称 MultiPro® 5CFLX Anti-Human CD163 (GHI/61)
别名 CD163, CD163 molecule, Hemoglobin scavenger receptor, M130, MM130, sCD163
计算分子量 1156 aa, 125 kDa
GenBank蛋白编号BC051281
基因名称 CD163
Gene ID (NCBI) 9332
ENSEMBL Gene IDENSG00000177575
RRIDAB_3673925
偶联类型 5CFLX
完整寡核苷酸序列CGGAGATGTGTATAAGAGACAGACCGCGACCTGATAACCCATATAAGAAA
条形码序列ACCGCGACCTGATAA
形式Liquid
UNIPROT IDQ86VB7
储存缓冲液 PBS with 1mM EDTA and 0.09% sodium azide , pH 7.3.
储存条件2-8°C Stable for one year after shipment.

背景介绍

CD163, also known as M130, is a membrane glycoprotein which belongs to the scavenger receptor superfamily (PMID: 8370408). It is an acute phase-regulated and signal-inducing macrophage protein expressed exclusively in monocytes and tissue macrophages (PMID: 11196644). CD163 mediates endocytosis of haptoglobin-haemoglobin complexes (PMID: 11196644). The uptake of haptoglobin by macrophages contributes to the recycling of iron and also to the inflammatory response (PMID: 22900885). Soluble CD163 (sCD163), as a result of ectodomain shedding during inflammatory activation of macrophages, circulates in blood and has been suggested as a plasma/serum marker for macrophage activity (PMID: 12570164).

Protocols

Our current MultiPro staining protocol for the cocktailDownload protocol
10x Genomics CG000149_Demonstrated Protocol CellSurface Protein Labeling_Rev D.pdfDownload protocol