MME,CD10 Monoclonal antibody
MME,CD10 Monoclonal Antibody for IHC,ELISA
Host / Isotype
Mouse / IgG2b
Reactivity
human
Applications
IHC,ELISA
Conjugate
Unconjugated
CloneNo.
1E7A11
验证数据展示
经过测试的应用
Positive IHC detected in | human kidney tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
Planning an IHC experiment? We recommend our IHCeasy CD10 Ready-To-Use IHC Kit. CD10 primary antibody included.
推荐稀释比
Application | Dilution |
---|---|
Immunohistochemistry (IHC) | IHC : 1:20-1:200 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
产品信息
60034-2-Ig targets MME,CD10 in IHC, ELISA applications and shows reactivity with human samples.
Tested Applications | IHC,ELISA |
Tested Reactivity | human |
Immunogen | MME,CD10 fusion protein Ag0427 种属同源性预测 |
Host / Isotype | Mouse / IgG2b |
Class | Monoclonal |
Type | Antibody |
Full Name | membrane metallo-endopeptidase |
Synonyms | |
Calculated Molecular Weight | 750 aa, 86 kDa |
GenBank Accession Number | BC101658 |
Gene Symbol | MME |
Gene ID (NCBI) | 4311 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Caprylic Acid/Ammonium Sulfate Precipitation |
UNIPROT ID | P08473 |
Storage Buffer | PBS with 0.1% sodium azide and 50% glycerol pH 7.3. |
Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
MME is also names as neprilysin,CALLA,NEP,SFE,CD10 and belongs to the peptidase M13 family.It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium.CD10 has been considered a useful marker in the diagnosis of renal carcinomas, because of its expression in clear cell and papillary renal cell carcinomas and its absence in chromophobe renal cell carcinomas(PMID:15286660).