LTBP2 Polyclonal antibody
LTBP2 Polyclonal Antibody for ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human and More (1)
Applications
ELISA and More (2)
Conjugate
Unconjugated
验证数据展示
发表文章中的应用
| WB | See 1 publications below |
| IHC | See 4 publications below |
产品信息
17708-1-AP targets LTBP2 in WB, IF, IHC, ELISA applications and shows reactivity with human samples.
| Tested Applications | ELISA |
| Cited Applications | WB, IHC |
| Tested Reactivity | human |
| Cited Reactivity | human, mouse |
| Immunogen | LTBP2 fusion protein Ag12007 种属同源性预测 |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Full Name | latent transforming growth factor beta binding protein 2 |
| Synonyms | C14orf141, LTBP 2, LTBP2, LTBP3, MSTP031 |
| Calculated Molecular Weight | 1821 aa, 195 kDa |
| GenBank Accession Number | BC078659 |
| Gene Symbol | LTBP2 |
| Gene ID (NCBI) | 4053 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q14767 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
LTBP2, a 240 kDa extracellular glycoprotein mapping to chromosome 14q24, belongs to a family of latent TGF-βbinding proteins (LTBPs) that regulates a well-known growth factor, TGF-β. LTBP2 is an elastic fiber-associating protein whose function in elastogenesis is not clear, as a DANCE binding Protein. It may play an integral structural role in elastic-fiber architectural organization and/or assembly. LTBP2 associates covalently with small latent TGF-beta complex via Repeat B and Repeat C. Defects in LTBP2 are the cause of primary congenital glaucoma type 3D (GLC3D). LTBP2 is a role in the structural stability of ciliary zonules, and growth and development of lens. LTBP2 null mutations in an autosomal recessive ocular syndrome with megalocornea, spherophakia, and secondary glaucoma. LTBP2 is a biomarker of heart failure.
发表文章
| Species | Application | Title |
|---|---|---|
Clin Sci (Lond) LTBP2 is secreted from lung myofibroblasts and is a potential biomarker for idiopathic pulmonary fibrosis. | ||
Am J Transl Res LTPB2 acts as a prognostic factor and promotes progression of cervical adenocarcinoma. | ||