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Iptakalim Hydrochloride

CAS号

642407-63-4

分子式

C9H22ClN

主要靶点

AChR|Potassium Channel

仅限科研使用

Cat No : CM11045

Print datasheet

Synonyms

Inhibitor|Iptakalim|Iptakalim Hydrochloride|KATP|KcsA|Potassium Channel|PotassiumChannel|potassium|PASMC|nAChR|Nicotinic acetylcholine receptors|Akt|channel|inhibit|eNOS

验证数据展示

  • CAS No.: 642407-63-4

    Iptakalim Hydrochloride
    CAS#: 642407-63-4

产品信息

CAS号 642407-63-4
分子式 C9H22ClN
主要靶点 AChR|Potassium Channel
主要通路 离子通道|神经科学
分子量 179.731
纯度 95%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
别名 Inhibitor|Iptakalim|Iptakalim Hydrochloride|KATP|KcsA|Potassium Channel|PotassiumChannel|potassium|PASMC|nAChR|Nicotinic acetylcholine receptors|Akt|channel|inhibit|eNOS

溶解度

DMSO:60 mg/mL (333.83 mM)

参考文献

1.Mengyu He, et al. Iptakalim ameliorates hypoxia-impaired human endothelial colony-forming cells proliferation, migration, and angiogenesis via Akt/eNOS pathways. Pulm Circ. 2019 Oct 18;9(3):2045894019875417.
2.Zhou HM, Zhong ML, Wang RH, Long CL, Zhang YF, Cui WY, Wang H. Synergisms of cardiovascular effects between iptakalim and amlodipine, hydrochlorothiazide or propranolol in anesthetized rats. Zhongguo Ying Yong Sheng Li Xue Za Zhi. 2015 Nov;31(6):532-40. PubMed PMID: 27215021.
3.Wang SY, Cui WY, Wang H. The new antihypertensive drug iptakalim activates ATP-sensitive potassium channels in the endothelium of resistance blood vessels. Acta Pharmacol Sin. 2015 Dec;36(12):1444-50. doi: 10.1038/aps.2015.97. Epub 2015 Nov 23. PubMed PMID: 26592519; PubMed Central PMCID: PMC4816240.
4.Fan Y, Kong H, Ye X, Ding J, Hu G. ATP-sensitive potassium channels: uncovering novel targets for treating depression. Brain Struct Funct. 2016 Jul;221(6):3111-22. doi: 10.1007/s00429-015-1090-z. Epub 2015 Aug 20. PubMed PMID: 26289962.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
×
=
×
C1   V1   C2   V2