ITGA6X1B Polyclonal antibody

ITGA6X1B Polyclonal Antibody for WB,ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB,ELISA and More (1)

Conjugate

Unconjugated

Cat No : 20232-1-AP

Print datasheet

Synonyms



经过测试的应用

Positive WB detected inmouse heart tissue, mouse kidney tissue

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:500-1:3000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

20232-1-AP targets ITGA6X1B in WB, IF, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications WB,ELISA
Cited ApplicationsWB, IF
Tested Reactivity human, mouse, rat
Cited Reactivityrat
Immunogen Peptide 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name integrin, alpha 6
Synonyms
Calculated Molecular Weight 127 kDa
Observed Molecular Weight 62 kDa
GenBank Accession NumberNM_001079818
Gene Symbol ITGA6
Gene ID (NCBI) 3655
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDP23229
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

ITGA6, also named asITGA6B, CD49f and VLA-6, belongs to the integrin alpha chain family. It is a receptor for laminin on platelets. ITGA6 is a receptor for laminin in epithelial cells and it plays a critical structural role in the hemidesmosome. Defects in ITGA6 are a cause of epidermolysis bullosa letalis with pyloric atresia (EB-PA) which also known as junctional epidermolysis bullosa with pyloric atresia (PA-JEB) or aplasia cutis congenita with gastrointestinal atresia. This antibody is specific to isoform Alpha-6X1X2B, isoform Alpha-6X1B and isoform Alpha-6X2B.

发表文章

SpeciesApplicationTitle
ratWB,IF

J Biomech

Integrin endocytosis on elastic substrates mediates mechanosensing.

Authors - Jing Li