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Host
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Species Reactivity
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Species Reactivity
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Conjugate
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Conjugate
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Compatible Species
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Conjugate
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验证数据展示

  • FC experiment of human peripheral blood leukocytes using 98343-1-RR

    FC experiment of human peripheral blood leukocytes using 98343-1-RR

    1x10^6 human peripheral blood leukocytes were surface stained with 0.25 ug Anti-Human IFNGR1/CD119 Rabbit RecAb (98343-1-RR, Clone: 242632A8) or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed.

  • FC experiment of human peripheral blood leukocytes using 98343-1-RR

    FC experiment of human peripheral blood leukocytes using 98343-1-RR

    1x10^6 human peripheral blood leukocytes were surface stained with 0.25 ug Anti-Human IFNGR1/CD119 Rabbit RecAb (98343-1-RR, Clone: 242632A8) (red) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed.

Anti-Human IFNGR1/CD119 Rabbit Recombinant Antibody

IFNGR1/CD119 Uni-rAbTM Recombinant Antibody for FC
Cat No. 98343-1-RR

产品说明书

CloneNo. 242632A8

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

FC

别名

IFNGR1, IFN-gamma receptor 1, IFN-gamma R1, IFN gamma receptor 1, IFN gamma R1

缓冲液配方:  PBS and Azide
PBS and Azide
PBS Only
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -

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经过测试的应用

Positive FC detected inhuman peripheral blood leukocytes

推荐稀释比

应用推荐稀释比
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

98343-1-RR targets IFNGR1/CD119 in FC applications and shows reactivity with human samples.

经测试应用 FC Application Description
经测试反应性 human
免疫原 Recombinant protein 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 interferon gamma receptor 1
别名 IFNGR1, IFN-gamma receptor 1, IFN-gamma R1, IFN gamma receptor 1, IFN gamma R1
计算分子量54 kDa
GenBank蛋白编号NM_000416.3
基因名称 IFNGR1
Gene ID (NCBI) 3459
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP15260-1
储存缓冲液 PBS with 0.09% sodium azide , pH 7.3
储存条件Store at 2 - 8°C. Stable for one year after shipment.

背景介绍

Interferon-gamam (IFN-γ) is a cytokine critical for innate and adaptive immunity against viral and intracellular bacterial infections and for tumor control. Cellular responses to IFN-γ are activated through its interaction with a heterodimeric receptor consisting of two subunits, IFNGR1 (CD119) and IFNGR2. IFNGR1 is the ligand-binding subunit which binds IFN-γ with high affinity, whereas IFNGR2 serves as the accessory subunit. Two subunits bind one IFN-γ dimer. Defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease (MSMD), also known as familial disseminated atypical mycobacterial infection. (PMID: 17981204; 946248; 10888113)

实验方案

Product Specific Protocols
FC protocol for IFNGR1/CD119 antibody 98343-1-RRDownload protocol
Standard Protocols
Click here to view our Standard Protocols