×
Use Able AI chat for product recommendations

验证数据展示

  • WB analysis of mouse liver using 16296-1-AP (same clone as 16296-1-PBS)

    WB analysis of mouse liver using 16296-1-AP (same clone as 16296-1-PBS)

    mouse liver mitochondria tissue were subjected to SDS PAGE followed by western blot with 16296-1-AP (GHITM antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 16296-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse brain using 16296-1-AP (same clone as 16296-1-PBS)

    IHC staining of mouse brain using 16296-1-AP (same clone as 16296-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 16296-1-AP (GHITM antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 16296-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse brain using 16296-1-AP (same clone as 16296-1-PBS)

    IHC staining of mouse brain using 16296-1-AP (same clone as 16296-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 16296-1-AP (GHITM antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 16296-1-PBS in a different storage buffer formulation.

  • IF Staining of HeLa using 16296-1-AP (same clone as 16296-1-PBS)

    IF Staining of HeLa using 16296-1-AP (same clone as 16296-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed HeLa cells using GHITM antibody (16296-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 16296-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO Validated

GHITM Polyclonal antibody, PBS Only

GHITM Polyclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA
Cat No. 16296-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, IHC, IF/ICC, Indirect ELISA

别名

Dermal papilla-derived protein 2, DERP2, Growth hormone-inducible transmembrane protein, MICS1, My021

缓冲液配方: 
偶联物:  Unconjugated
规格价格库存

点击咨询售前客服

点击咨询售后客服

产品信息

16296-1-PBS targets GHITM in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, IHC, IF/ICC, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原

CatNo: Ag9482

Product name: Recombinant human GHITM protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1-72 aa of BC010354

Sequence: MLAARLVCLRTLPSRVFHPAFTKASPVVKNSITKNQWLLTPSREYATKTRIGIRRGRTGQELKEAALEPSME

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 growth hormone inducible transmembrane protein
别名 Dermal papilla-derived protein 2, DERP2, Growth hormone-inducible transmembrane protein, MICS1, My021
计算分子量 345 aa, 37 kDa
观测分子量 42 kDa, 25-27 kDa
GenBank蛋白编号BC010354
基因名称 GHITM
Gene ID (NCBI) 27069
RRIDAB_2111275
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9H3K2
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

GHITM, also known as MICS1, TMBIM5 or DERP2, is a mitochondrial protein which localizes in the inner membrane. GHITM is involved in mitochondrial morphology in specific cristae structures and the apoptotic release of cytochrome c from the mitochondria (PMID: 18417609). The gene of GHITM maps to chromosome 10q23.1, and encodes a 345-amino-acid protein with a calculated molecular mass of 37 kDa. The apparent molecular weight has been reported to be 42 kDa, the increased size in the protein may be due to post-translational modifications (PMID: 11416014; 16412389). GHITM can be cleaved into smaller forms of 23-27 kDa (PMID: 16412389; 18417609).

||
New chat

Able™

正在加载，请稍候...