验证数据展示
产品信息
31264-1-PBS targets FOLR2 in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse samples.
| 经测试应用 | WB, IHC, IF/ICC, Indirect ELISA Application Description |
| 经测试反应性 | human, mouse |
| 免疫原 |
CatNo: Eg0953 Product name: recombinant human FOLR2 protein Source: mammalian cells-derived, pHZ-KIsec-C-6*HIS Tag: C-6*HIS Domain: 17-228 aa of NM_000803.5 Sequence: TMCSAQDRTDLLNVCMDAKHHKTKPGPEDKLHDQCSPWKKNACCTASTSQELHKDTSRLYNFNWDHCGKMEPACKRHFIQDTCLYECSPNLGPWIQQVNQSWRKERFLDVPLCKEDCQRWWEDCHTSHTCKSNWHRGWDWTSGVNKCPAGALCRTFESYFPTPAALCEGLWSHSYKVSNYSRGSGRCIQMWFDSAQGNPNEEVARFYAAAMH 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | folate receptor 2 (fetal) |
| 别名 | BETA HFR, FBP, FBP/PL 1, Folate receptor 2, folate receptor 2 (fetal) |
| 计算分子量 | 29KD |
| 观测分子量 | 33-35 kDa |
| GenBank蛋白编号 | NM_000803.5 |
| 基因名称 | FOLR2 |
| Gene ID (NCBI) | 2350 |
| RRID | AB_3669922 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity Purification |
| UNIPROT ID | P14207 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
FOLR2 (Folate Receptor 2), also known as Folate Receptor beta (FR-beta), is a 38 kDa glycoprotein that is anchored to the cell membrane via glycosyl phosphatidylinositol (GPI) linkage . FOLR2 belongs to the folate receptor (FOLR) family, which also includes FOLR1 (FR-α), FOLR3 (FR-γ), and FOLR4. FOLR2 has been shown to be expressed by malignant cells, including myelogenous leukemia cells, but has also been demonstrated to be mainly expressed by tumor-associated macrophages (TAMs).


