验证数据展示
经过测试的应用
| Positive WB detected in | mouse spleen tissue, mouse thymus tissue, rat spleen tissue, rat thymus tissue |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:500-1:1000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
33235-1-AP targets DcTRAILR1/TNFRSF23 in WB, ELISA applications and shows reactivity with mouse, rat samples.
| 经测试应用 | WB, ELISA Application Description |
| 经测试反应性 | mouse, rat |
| 免疫原 |
CatNo: Eg5262 Product name: recombinant mouse DcTRAILR1/TNFRSF23 protein Source: mammalian cells-derived, V37 Tag: C-rFc Domain: 30-155 aa of NM_024290.4 Sequence: MPESYSFNCPDGEYQSNDVCCKTCPSGTFVKAPCKIPHTQGQCEKCHPGTFTGKDNGLHDCELCSTCDKDQNMVADCSATSDRKCECQIGLYYYDPKFPESCRPCTKCPQGIPVLQECNSTANTVC 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | tumor necrosis factor receptor superfamily, member 23 |
| 别名 | Dctrailr1, Decoy TRAIL receptor 1, TNF receptor family member SOB, TNF receptor homolog 1, Tnfrh1 |
| 计算分子量 | 20 kDa |
| 观测分子量 | 24 kDa |
| GenBank蛋白编号 | NM_024290.4 |
| 基因名称 | Tnfrsf23 |
| Gene ID (NCBI) | 79201 |
| RRID | AB_3742908 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity Purification |
| UNIPROT ID | Q9ER63 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Decoy TRAIL receptor 1 (DcTRAILR1), also known as tumor necrosis factor receptor superfamily member 23 (TNFRSF23), is a GPI-anchored mouse TNF receptor superfamily member that lacks a cytoplasmic death domain. It is a decoy TRAIL receptor that can block TRAIL-induced apoptosis (PMID: 12466268). It has been reported that upregulation of DcTRAILR1 can prolong the lifespan of tumor-associated neutrophils (PMID: 39558859; 38207030).
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for DcTRAILR1/TNFRSF23 antibody 33235-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
