×
Use Able AI chat for product recommendations

验证数据展示

  • WB analysis of mouse liver using 18727-1-AP (same clone as 18727-1-PBS)

    WB analysis of mouse liver using 18727-1-AP (same clone as 18727-1-PBS)

    mouse liver tissue were subjected to SDS PAGE followed by western blot with 18727-1-AP (DNA2 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 18727-1-PBS in a different storage buffer formulation.

  • IP experiment of mouse liver using 18727-1-AP (same clone as 18727-1-PBS)

    IP experiment of mouse liver using 18727-1-AP (same clone as 18727-1-PBS)

    IP result of anti-DNA2 (IP:18727-1-AP, 4ug; Detection:18727-1-AP 1:300) with mouse liver tissue lysate 4800 ug. This data was developed using the same antibody clone with 18727-1-PBS in a different storage buffer formulation.

  • IHC staining of human cervical cancer using 18727-1-AP (same clone as 18727-1-PBS)

    IHC staining of human cervical cancer using 18727-1-AP (same clone as 18727-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human cervical cancer tissue slide using 18727-1-AP (DNA2 antibody) at dilution of 1:200 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 18727-1-PBS in a different storage buffer formulation.

  • IHC staining of human cervical cancer using 18727-1-AP (same clone as 18727-1-PBS)

    IHC staining of human cervical cancer using 18727-1-AP (same clone as 18727-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human cervical cancer tissue slide using 18727-1-AP (DNA2 antibody) at dilution of 1:200 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 18727-1-PBS in a different storage buffer formulation.

  • IHC staining of human cervical cancer using 18727-1-AP (same clone as 18727-1-PBS)

    IHC staining of human cervical cancer using 18727-1-AP (same clone as 18727-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human cervical cancer tissue slide using 18727-1-AP (DNA2 antibody) at dilution of 1:200 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 18727-1-PBS in a different storage buffer formulation.

  • IF Staining of HepG2 using 18727-1-AP (same clone as 18727-1-PBS)

    IF Staining of HepG2 using 18727-1-AP (same clone as 18727-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed HepG2 cells using DNA2 antibody (18727-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L) (SA00013-2), CL594-Phalloidin (red). This data was developed using the same antibody clone with 18727-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO Validated

DNA2 Polyclonal antibody, PBS Only

DNA2 Polyclonal Antibody for WB, IHC, IF/ICC, IP, Indirect ELISA
Cat No. 18727-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, IHC, IF/ICC, IP, Indirect ELISA

别名

DNA2L, KIAA0083

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

点击咨询售前客服

点击咨询售后客服

产品信息

18727-1-PBS targets DNA2 in WB, IHC, IF/ICC, IP, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, IHC, IF/ICC, IP, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原

Peptide

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 DNA replication helicase 2 homolog (yeast)
别名 DNA2L, KIAA0083
计算分子量 120 kDa
观测分子量 120-130 kDa
GenBank蛋白编号NM_001080449
基因名称 DNA2
Gene ID (NCBI) 1763
RRIDAB_10637998
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDP51530
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

DNA2(DNA replication ATP-dependent helicase/nuclease DNA2) is also named as DNA2L, KIAA0083 and belongs to the DNA2/NAM7 helicase family. This protein includes 2 domains: DNA replication nuclease and DNA replication ATP-dependent helicase. It is a conserved helicase/nuclease involved in the maintenance of mitochondrial and nuclear DNA stability and it can interact with DNA polymerase gamma and stimulating its activity. It can also process intermediate 5' flap structures occuring in DNA replication long-patch base excision repair in mitochondria. It has 4 isoforms produced by alternative splicing. This antibody is specific to DNA2.

||
New chat

Able™

正在加载，请稍候...