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验证数据展示

  • WB analysis using 22184-1-AP (same clone as 22184-1-PBS)

    WB analysis using 22184-1-AP (same clone as 22184-1-PBS)

    mouse heart tissue was subjected to SDS PAGE followed by western blot with 22184-1-AP (Connexin 45 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 22184-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse brain using 22184-1-AP (same clone as 22184-1-PBS)

    IHC staining of mouse brain using 22184-1-AP (same clone as 22184-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 22184-1-AP (Connexin 45 antibody) at dilution of 1:400 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 22184-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO验证

Connexin 45 Polyclonal antibody, PBS Only

Connexin 45 Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 22184-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, IHC, Indirect ELISA

别名

Connexin-45, Cx45, Gap junction alpha-7 protein, Gap junction gamma-1 protein, GJA7

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

22184-1-PBS targets Connexin 45 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原 Connexin 45 fusion protein Ag16742 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 gap junction protein, gamma 1, 45kDa
别名 Connexin-45, Cx45, Gap junction alpha-7 protein, Gap junction gamma-1 protein, GJA7
计算分子量 396 aa, 45 kDa
观测分子量45 kDa
GenBank蛋白编号BC096213
基因名称 Connexin-45
Gene ID (NCBI) 10052
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDP36383
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Connexin 45 (Cx45), also known as Gap junction gamma protein (GJC1), belongs to the connexin family. Connexins are membrane-spanning proteins that assemble to form gap junction channels that facilitate the transfer of ions and small molecules between cells. A loss-of-function mutation in Cx45 contributing to Atrial fibrillation (AF) and other cardiac arrhythmias (PMID: 33429106).