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Host
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Species Reactivity
0
Species Reactivity
0
Conjugate
0
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Compatible Species
0
Conjugate
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验证数据展示

  • WB analysis using 10170-1-AP (same clone as 10170-1-PBS)

    WB analysis using 10170-1-AP (same clone as 10170-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 10170-1-AP (Complement factor B antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 10170-1-PBS in a different storage buffer formulation.

  • IHC staining of human liver using 10170-1-AP (same clone as 10170-1-PBS)

    IHC staining of human liver using 10170-1-AP (same clone as 10170-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 10170-1-AP (Complement factor B antibody) at dilution of 1:400 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 10170-1-PBS in a different storage buffer formulation.

  • IHC staining of human liver using 10170-1-AP (same clone as 10170-1-PBS)

    IHC staining of human liver using 10170-1-AP (same clone as 10170-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 10170-1-AP (Complement factor B antibody) at dilution of 1:400 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 10170-1-PBS in a different storage buffer formulation.

Complement factor B Polyclonal antibody, PBS Only

Complement factor B Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 10170-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, rat

应用

WB, IHC, Indirect ELISA

别名

CFB, Complement factor B Ba fragment, CFAB, C3/C5 convertase, BFD

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

10170-1-PBS targets Complement factor B in WB, IHC, Indirect ELISA applications and shows reactivity with human, rat samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, rat
免疫原 Complement factor B fusion protein Ag0226 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 complement factor B
别名 CFB, Complement factor B Ba fragment, CFAB, C3/C5 convertase, BFD
计算分子量 86 kDa
观测分子量 93-100 kDa, 60-69 kDa
GenBank蛋白编号BC007990
基因名称 Complement factor B
Gene ID (NCBI) 629
RRIDAB_2082384
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDP00751
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Complement factor B (CFB) is a component of the alternative pathway of complement activation. Complement factor B is a 93-100 kDa glycoprotein and is cleaved into Ba (33 kDa) and Bb (60 kDa) by factor D in the presence of C3b (PMID: 11025450). The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation. This antibody raised against 573-761aa of human complement factor B can recognize complement factor B and Bb fragment.