验证数据展示
产品信息
83370-1-PBS targets MCP-1/CCL2 in Cytometric bead array, Indirect ELISA applications and shows reactivity with rat samples.
| 经测试应用 | Cytometric bead array, Indirect ELISA Application Description |
| 经测试反应性 | rat |
| 免疫原 | MCP-1/CCL2 fusion protein Eg0397 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | chemokine (C-C motif) ligand 2 |
| 别名 | Ccl2, C-C motif chemokine 2, CCL 2, CCL-2, chemokine (C C motif) ligand 2 |
| 计算分子量 | 16 kDa |
| GenBank蛋白编号 | NM_031530 |
| 基因名称 | MCP-1/CCL2 |
| Gene ID (NCBI) | 24770 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | P14844 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Monocyte chemoattractant protein-1 (MCP-1/CCL2) is one of the key chemokines that regulate migration and infiltration of monocytes/macrophages. Both CCL2 and its receptor CCR2 have been demonstrated to be induced and involved in various diseases. Migration of monocytes from the blood stream across the vascular endothelium is required for routine immunological surveillance of tissues, as well as in response to inflammation.