验证数据展示
产品信息
51024-1-AP targets CXCR7 in WB, IF, FC, IHC, ELISA applications and shows reactivity with human, mouse, rat samples.
| 经测试应用 | ELISA Application Description |
| 文献引用应用 | WB, IF, FC, IHC |
| 经测试反应性 | human, mouse, rat |
| 文献引用反应性 | human, mouse, rat |
| 免疫原 |
Peptide 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | chemokine (C-X-C motif) receptor 7 |
| 别名 | |
| 计算分子量 | 362 aa, 41 kDa |
| 观测分子量 | 50 kDa |
| GenBank蛋白编号 | BC036661 |
| 基因名称 | CXCR7 |
| Gene ID (NCBI) | 57007 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | P25106 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| 储存条件 | Store at -20°C. Aliquoting is unnecessary for -20oC storage. |
背景介绍
CXCR7, also named as CMKOR1, GPR159 and RDC1, belongs to the G-protein coupled receptor 1 family. It is a receptor for CXCL12/SDF1. CXCR7 acts as coreceptor with CXCR4 for a restricted number of HIV isolates. CXCR7 was shown to contribute to neoangiogenesis in prostate cancer and to promote tumor cell proliferation in breast cancer and adenocarcinoma of the lung.
发表文章
| Species | Application | Title |
|---|---|---|
Biomaterials The effect of stromal cell-derived factor-1α/heparin coating of biodegradable vascular grafts on the recruitment of both endothelial and smooth muscle progenitor cells for accelerated regeneration. | ||
Mod Pathol Strong expression of CXCL12 is associated with a favorable outcome in osteosarcoma. | ||
J Biol Chem Molecular mechanisms for enhancement of stromal cell-derived factor 1-induced chemotaxis by platelet endothelial cell adhesion molecule 1 (PECAM-1). | ||
PLoS One Expression of the Chemokine Receptor CXCR7 in CXCR4-Expressing Human 143B Osteosarcoma Cells Enhances Lung Metastasis of Intratibial Xenografts in SCID Mice. | ||
Scand J Gastroenterol CXCR7 as a chemokine receptor for SDF-1 promotes gastric cancer progression via MAPK pathways. |
