验证数据展示
经过测试的应用
| Positive IHC detected in | human breast cancer tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
Planning an IHC experiment? We recommend our IHCeasy CLDN7 Ready-To-Use IHC Kit. CLDN7 primary antibody included.
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Immunohistochemistry (IHC) | IHC : 1:200-1:800 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
发表文章中的应用
| IHC | See 1 publications below |
| IF | See 6 publications below |
产品信息
10118-1-AP targets Claudin 7 in IHC, IF, ELISA applications and shows reactivity with human, mouse samples.
| 经测试应用 | IHC, ELISA Application Description |
| 文献引用应用 | IHC, IF |
| 经测试反应性 | human, mouse |
| 文献引用反应性 | human, mouse |
| 免疫原 | Claudin 7 fusion protein Ag0159 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | claudin 7 |
| 别名 | CEPTRL2, Claudin 7, CLDN 7, CLDN7, CPETRL2, Hs.84359 |
| 计算分子量 | 22.4 kDa |
| 观测分子量 | 23 kDa |
| GenBank蛋白编号 | BC001055 |
| 基因名称 | Claudin 7 |
| Gene ID (NCBI) | 1366 |
| RRID | AB_2083302 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | O95471 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Claudins are a family of proteins that are the most important components of tight junctions, where they establish the paracellular barrier that controls the flow of molecules in the intercellular space between the cells of an epithelium. They are small (20-27 kilodalton (kDa)) proteins with very similar structures. They have four transmembrane domains, with the N-terminus and the C-terminus in the cytoplasm.
实验方案
| Product Specific Protocols | |
|---|---|
| IHC protocol for Claudin 7 antibody 10118-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
发表文章
| Species | Application | Title |
|---|---|---|
Cancers (Basel) Targeting PVT1 Exon 9 Re-Expresses Claudin 4 Protein and Inhibits Migration by Claudin-Low Triple Negative Breast Cancer Cells. | ||
iScience Commercial dishes with gelatin-free microstructured inserts for elongated stem cell self-renewal and pluripotency | ||
Stem Cell Res Ther Human menstrual blood-derived stem cell transplantation suppresses liver injury in DDC-induced chronic cholestasis. | ||
FASEB J Steroid receptor coactivator-2 drives epithelial reprogramming that enables murine embryo implantation | ||
Front Pharmacol Berberine Improves Irinotecan-Induced Intestinal Mucositis Without Impairing the Anti-colorectal Cancer Efficacy of Irinotecan by Inhibiting Bacterial β-glucuronidase. | ||
Biol Reprod Pre-implantation triclosan exposure alters uterine receptivity through affecting tight junction protein†. |
