CIRBP Monoclonal antibody
CIRBP Monoclonal Antibody for ELISA
Host / Isotype
Mouse / IgM
Reactivity
human, mouse
Applications
ELISA and More (1)
Conjugate
Unconjugated
CloneNo.
4D12H7
验证数据展示
Planning an IHC experiment? We recommend our IHCeasy CIRBP Ready-To-Use IHC Kit. CIRBP primary antibody included.
发表文章中的应用
| IHC | See 1 publications below |
产品信息
60025-2-Ig targets CIRBP in IHC, ELISA applications and shows reactivity with human, mouse samples.
| Tested Applications | ELISA |
| Cited Applications | IHC |
| Tested Reactivity | human, mouse |
| Cited Reactivity | human |
| Immunogen | CIRBP fusion protein Ag0280 种属同源性预测 |
| Host / Isotype | Mouse / IgM |
| Class | Monoclonal |
| Type | Antibody |
| Full Name | cold inducible RNA binding protein |
| Synonyms | |
| Calculated Molecular Weight | 172 aa, 19 kDa |
| Observed Molecular Weight | 19 kDa |
| GenBank Accession Number | BC000403 |
| Gene Symbol | CIRBP |
| Gene ID (NCBI) | 1153 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Caprylic acid/ammonium sulfate precipitation |
| UNIPROT ID | Q14011 |
| Storage Buffer | PBS with 0.1% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
CIRBP, also named as A18HNRNP and CIRP, is a cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. CIRBP is also involved in cap-independent translation upon moderate cold-shock. It acts as a translational activator. CIRBP is a suppressive rather stimulatory effect on proliferation. It acts as a translational repressor. CIRBP is an immortalized gene in murine primary cells. CIRBP promotes assembly of stress granules (SGs), when overexpressed. It is a potential proto-oncogenic proteins upon overexpression.(PMID:19900510) Suppression of CIRBP increased the apoptotic cell population of neural stem cells at moderate low temperature. (PMID:20735994) This antibody can bind the close sequences genes. This antibody is a mouse monoclonal antibody raised against full length CIRBP of human origin.
发表文章
| Species | Application | Title |
|---|---|---|
Ann Dermatol Expression of Cold-Inducible RNA-Binding Protein in Normal Skin, Actinic Keratosis and Squamous Cell Carcinoma. |
