验证数据展示
产品信息
16192-1-AP targets CD68-Specific in WB, IF, IHC, ELISA applications and shows reactivity with human, mouse samples.
| 经测试应用 | ELISA Application Description |
| 文献引用应用 | WB, IF, IHC |
| 经测试反应性 | human, mouse |
| 文献引用反应性 | human, mouse |
| 免疫原 |
Peptide 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | CD68 molecule |
| 别名 | CD68, CD68 molecule, GP110, Macrosialin, SCARD1 |
| 计算分子量 | 37 kDa |
| 观测分子量 | 100-110 kDa, 60-70 kDa |
| GenBank蛋白编号 | NM_001251 |
| 基因名称 | CD68 |
| Gene ID (NCBI) | 968 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | P34810 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
CD68 is a type I transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It belongs to the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family and primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. CD68 is also a member of the scavenger receptor family. It may play a role in phagocytic activities of tissue macrophages. This antibody is raised against a synthetic peptide (FPYGHLSFGFMQDLC) of human CD68.
发表文章
| Species | Application | Title |
|---|---|---|
J Am Heart Assoc Increased Atherosclerotic Lesions in LDL Receptor Deficient Mice With Hematopoietic Nuclear Receptor Rev-erbα Knock- Down. | ||
PLoS One Loss of Metabotropic Glutamate Receptor 5 Function on Peripheral Benzodiazepine Receptor in Mice Prenatally Exposed to LPS. | ||
J Vis Exp Development and Identification of a Novel Subpopulation of Human Neutrophil-derived Giant Phagocytes In Vitro. |