验证数据展示
产品信息
98306-6-PBS targets CD38 in FC applications and shows reactivity with rabbit samples.
| 经测试应用 | FC Application Description |
| 经测试反应性 | rabbit |
| 免疫原 |
CatNo: Eg2484 Product name: recombinant rabbit CD38 protein Source: mammalian cells-derived, pHZ-KIsec-C-6*HIS Tag: C-6*HIS Sequence: / 种属同源性预测 |
| 宿主/亚型 | Mouse / IgG2a |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | CD38 |
| 别名 | ADP ribosyl cyclase/cyclic ADP ribose hydrolase, ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1, CD38 antigen, Cyclic ADP ribose hydrolase 1 |
| 基因名称 | CD38 |
| Gene ID (NCBI) | 100009409 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | Q9MZ03 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
CD38, also known as ADP-ribosyl cyclase 1, is a type II transmembrane glycoprotein with a short N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites (PMID: 2319135). The extracellular domain of CD38 has bifunctional enzyme activities that catalyze synthesis of cyclic ADP ribose from nicotinamide adenine dinucleotide (NAD) and hydrolysis of cyclic ADP ribose to adenosine diphosphoribose (PMID: 10636863). CD38 is expressed on a variety of hematopoietic and non-hematopoietic cells and is involved in diverse processes such as generation of calcium-mobilizing metabolites, cell activation, and chemotaxis (PMID: 25938500).
