验证数据展示
产品信息
87659-1-PBS targets GGT1 as part of a matched antibody pair:
MP03153-1: 87659-3-PBS capture and 87659-1-PBS detection (validated in Cytometric bead array)
Unconjugated rabbit recombinant monoclonal antibody in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation. Created using Proteintech’s proprietary in-house recombinant technology. Recombinant production enables unrivalled batch-to-batch consistency, easy scale-up, and future security of supply.
This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.
| 经测试应用 | WB, Cytometric bead array, Indirect ELISA Application Description |
| 经测试反应性 | mouse, rat |
| 免疫原 |
CatNo: Eg6301 Product name: Recombinant mouse CD224/GGT1 protein Source: mammalian cells-derived, V37 Tag: C-rFc Domain: 27-568 aa of NM_001305992.1 Sequence: PYTSGKPDHVYSRAAVATDAKRCSEIGRDILQEGGSVVDAAIASLLCMGLMNAHSMGIGGGLFFTIYNSTTGKVEVINAREVAPRLANTTMFNNSKDSEEGGLSVAVPGEIRGYELAHQRHGRLPWARLFQPSIQLARHGFPVGKGLAIALDKKRDVIEKTPALCEVFCRQGKVLQEGETVTMPKLADTLQILAQEGAKAFYNGSLTAQIVKDIQEAGGIMTVEDLNNYRAELIEHPMSIGLGDATLYVPSAPLSGPVLILILNILKGYNFSPKSVATPEQKALTYHRIVEAFRFAYAKRTMLGDPKFVDVSQVIRNMSSEFYATQLRARITDETTHPAAYYEPEFYLQDDGGTAHLSAVSEDGSAVAATSTINLYFGSKVLSRVSGILFNDEMDDFSSPNFINQFRVAPSPANFIKPGKQPLSSMCPSIILDKDGQVRMVVGASGGTQITTSVALAIINSLWFGYDVKRAVEEPRLHNQLLPNTTTVEKDIDQVVTAGLKIRHHHTEVTPTFIAVVQAVVRASGGWAAASDSRKGGEPAGY 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | gamma-glutamyltransferase 1 |
| 别名 | CD224, EC:2.3.2.2, EC:3.4.19.13, EC:3.4.19.14, Gamma-glutamyltransferase 1 |
| 计算分子量 | 62 kDa |
| 观测分子量 | 50-61 kDa |
| GenBank蛋白编号 | NM_001305992.1 |
| 基因名称 | Ggt1 |
| Gene ID (NCBI) | 14598 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | Q60928 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
GGT1 is a heterodimer composed of light chain and heavy chain, and its active site is located in the light chain. The metabolism of glutathione by GGT1 releases free glutamic acid and dipeptide cysteine-glycine, which can be hydrolyzed into cysteine and glycine by dipeptidase. In the presence of high concentration of dipeptide and some amino acids, it can also catalyze the peptide transfer reaction and transfer γ -glutamyl group to receptor amino acids to form new γ -glutamyl compounds. Participate in cysteine homeostasis, glutathione homeostasis and the transformation of leukotriene LTC4 to LTD4 (PMID:12810527).
