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CD200R1 Polyclonal antibody

CD200R1 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

Human

Applications

WB, ELISA

Conjugate

Unconjugated

Cat No : 30013-1-AP

Print datasheet

Synonyms

CD200 receptor 1, CD200R, CD200R1, CRTR2, HCRTR2, MOX2R, OX2R

验证数据展示

  • WB analysis using 30013-1-AP

    WB analysis using 30013-1-AP

    Various lysates were subjected to SDS PAGE followed by western blot with 30013-1-AP (CD200R1 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

经过测试的应用

Positive WB detected inA549 cells, K-562 cells, PC-3 cells

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:500-1:1000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

30013-1-AP targets CD200R1 in WB, ELISA applications and shows reactivity with Human samples.

Tested Applications WB, ELISA
Tested Reactivity Human
Immunogen fusion protein 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name CD200 receptor 1
Synonyms CD200 receptor 1, CD200R, CD200R1, CRTR2, HCRTR2, MOX2R, OX2R
Observed Molecular Weight 33-36 kDa
GenBank Accession NumberBC069743
Gene Symbol CD200R1
Gene ID (NCBI) 131450
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ8TD46
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Cell surface glycoprotein CD200 receptor 1 (CD200R1) is also named as CD200R, CRTR2, MOX2R and OX2R, and belongs to the CD200R family. CD200R1 is inhibitory receptor for the CD200/OX2 cell surface glycoprotein. CD200R1 is highly glycosylated, containing ten potential N-glycosylation sites (PMID: 15187158). CD200R1 limits inflammation by inhibiting the expression of pro-inflammatory molecules including TNF-alpha, interferons, and inducible nitric oxide synthase (iNOS) in response to selected stimuli. As an immune inhibitory molecule, CD200R1 binds to CD200, ultimately leading to inhibition of classical activation of macrophages and microglia (PMID: 24588829).

实验方案

Product Specific Protocols
WB protocol for CD200R1 antibody 30013-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols