验证数据展示
产品信息
83184-1-PBS targets CD160 as part of a matched antibody pair:
MP00237-1: 83184-1-PBS capture and 83184-2-PBS detection (validated in Cytometric bead array)
Unconjugated rabbit recombinant monoclonal antibody in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation. Created using Proteintech’s proprietary in-house recombinant technology. Recombinant production enables unrivalled batch-to-batch consistency, easy scale-up, and future security of supply.
This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.
| 经测试应用 | Cytometric bead array, Indirect ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 | CD160 fusion protein Ag1754 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 亲和力 | KD=2.67 x 10-10M KOff=8.00 x 10-5M KOn=2.99 x 105M |
| 全称 | CD160 molecule |
| 别名 | NK1, CD160 molecule, CD160 antigen, soluble form, CD160 antigen, BY55 |
| 计算分子量 | 20 kDa |
| GenBank蛋白编号 | BC014465 |
| 基因名称 | CD160 |
| Gene ID (NCBI) | 11126 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | O95971 |
| 储存缓冲液 | PBS only , pH 7.3 |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
CD160 is a glycosylphosphatidylinositol (GPI)-anchored protein that is expressed on almost all intestinal intraepithelial lymphocytes (IELs), gamma delta T cells, CD56 (dim) CD16+ cytotoxic NK cells, and a minor subset of CD4+ and CD8+ T cells (PMID: 31332204; 25179432). The binding of CD160 to both classical and non-classical MHC I enhances NK and CD8+ cytotoxic T lymphocyte functions (PMID: 25179432). CD160 is a ligand for HVEM (herpes virus entry mediator) and the binding of CD160 to HVEM inhibits T cell activity (PMID: 19426226).