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IBT6A

CAS号

1022150-12-4

分子式

C22H22N6O

主要靶点

BTK

仅限科研使用

Cat No : CM00870

Print datasheet

Synonyms

inhibit|IBT6A|IBT-6A|Bruton tyrosine kinase|Btk|BTK|Inhibitor|依鲁替尼中间体

验证数据展示

  • CAS No.: 1022150-12-4

    IBT6A
    CAS#: 1022150-12-4

产品信息

CAS号 1022150-12-4
分子式 C22H22N6O
主要靶点 BTK
主要通路 血管生成|蛋白酪氨酸激酶
分子量 386.45
纯度 99.88%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 keep away from direct sunlight,keep away from moisture,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
别名 inhibit|IBT6A|IBT-6A|Bruton tyrosine kinase|Btk|BTK|Inhibitor|依鲁替尼中间体

溶解度

DMSO:25 mg/mL (64.69 mM)

参考文献

1.Somana Siva Prasad, et al. A QUALITY BY DESIGN APPROACH FOR DEVELOPMENT OF SIMPLE AND ROBUST REVERSED PHASE STABILITY INDICATING HPLC METHOD FOR ESTIMATION OF IBRUTINIB AND ITS IMPURITIES.
2.Honigberg LA, et al. The Bruton tyrosine kinase inhibitor PCI-32765 blocks B-cell activation and is efficacious in models of autoimmune disease and B-cell malignancy. Proc Natl Acad Sci U S A. 2010 Jul 20;107(29):13075-80.
3.Liu N, et al. Direct and two-step bioorthogonal probes for Bruton's tyrosine kinase based on ibrutinib: a comparative study. Org Biomol Chem. 2015 May 14;13(18):5147-57.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
=
×
×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
×
=
×
C1   V1   C2   V2