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验证数据展示

  • IHC staining of human colon cancer using 51009-2-AP (same clone as 51009-2-PBS)

    IHC staining of human colon cancer using 51009-2-AP (same clone as 51009-2-PBS)

    Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using 51009-2-AP (BRD7 antibody) at dilution of 1:100 (under 10x lens). This data was developed using the same antibody clone with 51009-2-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with BRD7 antibody included
  • IHC staining of human cervical cancer using 51009-2-AP (same clone as 51009-2-PBS)

    IHC staining of human cervical cancer using 51009-2-AP (same clone as 51009-2-PBS)

    Immunohistochemical analysis of paraffin-embedded human cervical cancer tissue slide using 51009-2-AP (BRD7 Antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 51009-2-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with BRD7 antibody included
  • WB analysis using 51009-2-AP (same clone as 51009-2-PBS)

    WB analysis using 51009-2-AP (same clone as 51009-2-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 51009-2-AP (BRD7 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 51009-2-PBS in a different storage buffer formulation.

  • WB analysis using 51009-2-AP (same clone as 51009-2-PBS)

    WB analysis using 51009-2-AP (same clone as 51009-2-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 51009-2-AP (BRD7 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 51009-2-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO验证

BRD7 Polyclonal antibody, PBS Only

BRD7 Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 51009-2-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, Indirect ELISA

别名

缓冲液配方:  PBS Only
PBS, Azide, Glycerol
PBS Only
偶联物:  Unconjugated
规格价格库存

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Planning an IHC experiment? We recommend our IHCeasy BRD7 Ready-To-Use IHC Kit. BRD7 primary antibody included.

产品信息

51009-2-PBS targets BRD7 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原

CatNo: Ag3911

Product name: Recombinant human BRD7 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1-353 aa of BC050728

Sequence: MGKKHKKHKSDKHLYEEYVEKPLKLVLKVGGNEVTELSTGSSGHDSSLFEDKNDHDKHKDRKRKKRKKGEKQIPGEEKGRKRRRVKEDKKKRDRDRVENEAEKDLQCHAPVRLDLPPEKPLTSSLAKQEEVEQTPLQEALNQLMRQLQRKDPSAFFSFPVTDFIAPGYSMIIKHPMDFSTMKEKIKNNDYQSIEELKDNFKLMCTNAMIYNKPETIYYKAAKKLLHSGMKILSQERIQSLKQSIDFMADLQKTRKQKDGTDTSQSGEDGGCWQREREDSGDAEAHAFKSPSKENKKKDKDMLEDKFKSNNLEREQEQLDRIVKESGGKLTRRLVNSQCEFERRKPDGTTTLGL

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 bromodomain containing 7
别名
计算分子量 651 aa, 74 kDa
观测分子量 70-74 kDa
GenBank蛋白编号BC050728
基因名称 BRD7
Gene ID (NCBI) 29117
RRIDAB_2259226
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9NPI1
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

BRD7 (bromodomain containing 7), is a subunit of poly-bromo-associated BRG1-associated factor (PBAF)-specific Swi/Snf chromatin remodeling complexes.BRD7 is proposed as a tumor suppressor protein, since its identification as an important component of both functional p53 and BRCA1 (breast cancer 1, early onset) pathways. BRD7 could down-regulate the GSK3beta phosphotransferase activity as dephosphorylation of GSK3B at 'Tyr-216', thus activate the Wnt signaling pathway in a DVL1-dependent manner.

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