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Adenine monohydrochloride hemihydrate

CAS号

6055-72-7

分子式

C5H8ClN5O

主要靶点

Adenosine Receptor|Endogenous Metabolite

仅限科研使用

Cat No : CM01523

Print datasheet

Synonyms

腺嘌呤盐酸盐|腺嘌呤盐酸盐水合物?|Inhibitor|inhibit|EndogenousMetabolite|Endogenous Metabolite|6-Aminopurine hydrochloride hydrate|6-Aminopurine hydrochloride Hydrate|Adenosine Receptor|AdenosineReceptor|Adenosine receptor|Adenine|Adenine hydrochloride Hydrate|Adenine hydrochloride hydrate|Adenine monohydrochloride hemihydrate|Adenine monohydrochloride Hemihydrate

验证数据展示

  • CAS No.: 6055-72-7

    Adenine monohydrochloride hemihydrate
    CAS#: 6055-72-7

产品信息

CAS号 6055-72-7
分子式 C5H8ClN5O
主要靶点 Adenosine Receptor|Endogenous Metabolite
主要通路 G 蛋白偶联受体|神经科学|代谢
分子量 189.6
纯度 97.61%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
别名 腺嘌呤盐酸盐|腺嘌呤盐酸盐水合物?|Inhibitor|inhibit|EndogenousMetabolite|Endogenous Metabolite|6-Aminopurine hydrochloride hydrate|6-Aminopurine hydrochloride Hydrate|Adenosine Receptor|AdenosineReceptor|Adenosine receptor|Adenine|Adenine hydrochloride Hydrate|Adenine hydrochloride hydrate|Adenine monohydrochloride hemihydrate|Adenine monohydrochloride Hemihydrate

靶点活性

Adenosine receptor:18 nM (Ki)

体内活性

Procyclidine因其抗胆碱作用被用作抗帕金森病药物，同时也因具有NMDA拮抗特性而被认为有用。与其他NMDA拮抗剂不同，这种药物由于其抗胆碱作用，不具有神经毒性副作用[1]。

溶解度

DMSO:50 mg/mL (263.71 mM)

参考文献

1.Gorzalka S, et al. Evidence for the functional expression and pharmacological characterization of adenine receptors in native cells and tissues. Mol Pharmacol. 2005 Mar;67(3):955-64.
2.Bender E, et al. Characterization of an orphan G protein-coupled receptor localized in the dorsal root ganglia reveals adenine as a signaling molecule. Proc Natl Acad Sci U S A. 2002 Jun 25;99(13):8573-8.

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