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ASXL1 Polyclonal antibody

ASXL1 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, ELISA

Conjugate

Unconjugated

Cat No : 27042-1-AP

Print datasheet

Synonyms

ASXL1, KIAA0978

验证数据展示

  • WB analysis using 27042-1-AP

    WB analysis using 27042-1-AP

    K-562 cells were subjected to SDS PAGE followed by western blot with 27042-1-AP (ASXL1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

经过测试的应用

Positive WB detected inK-562 cells

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:500-1:2000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

27042-1-AP targets ASXL1 in WB, ELISA applications and shows reactivity with human samples.

Tested Applications WB, ELISA
Tested Reactivity human
Immunogen ASXL1 fusion protein Ag25874 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name additional sex combs like 1 (Drosophila)
Synonyms ASXL1, KIAA0978
Observed Molecular Weight90 kDa
GenBank Accession NumberBC137278
Gene Symbol ASXL1
Gene ID (NCBI) 171023
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ8IXJ9
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Additional sex combs-like 1 (ASXL1) is a member of the ASXL family, which is involved in epigenetic regulation. It is one of the mammalian Asx homologs. Mutations in the ASXL1 gene are frequently found in myeloid neoplasms, breast cancers and prostate cancers (PMID: 30013160; PMID: 22436456; PMID: 26470845). In patients with myeloid malignancies, ASXL1 mutations are mostly heterozygous frameshift or nonsense mutations that result in C-terminal truncation (PMID: 30982744; PMID: 26095772; PMID: 32683582; PMID: 29643185).

实验方案

Product Specific Protocols
WB protocol for ASXL1 antibody 27042-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols