ARF6 Polyclonal antibody

ARF6 Polyclonal Antibody for IHC,ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

IHC,ELISA

Conjugate

Unconjugated

Cat No : 18119-1-AP

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Synonyms

ADP ribosylation factor 6, ARF6



产品信息

The immunogen of 18119-1-AP is ARF6 Fusion Protein expressed in E. coli.

Tested Applications IHC,ELISA
Tested Reactivity human, mouse, rat
Immunogen ARF6 fusion protein Ag12642 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name ADP-ribosylation factor 6
Synonyms ADP ribosylation factor 6, ARF6
Calculated Molecular Weight 20 kDa
GenBank Accession NumberBC002952
Gene Symbol ARF6
Gene ID (NCBI) 382
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDP62330
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

ADP-ribosylation factors (ARFs) are members of the ARF family of GTP-binding proteins of the Ras superfamily, with 20kda protein size. ARFs bind and regulate GTP/GDP cycle by alternating between the active GTP-bound and inactive GDP-bound conformations. ARF family proteins are essential and ubiquitous in eukaryotes. Six highly conserved members of the family have been identified in mammalian cells. They function in vesicular traffic and actin remodelling and other bioprocesses in cells. The ARF6 is one of best identified ARFs It is present at the plasma membrane and to some extent on endosomal membranes where it regulates the flow of trafficking into and out of the cell and the actin cytoskeleton. (PMID: 7759471, PMID: 16042562). This antibody can bind ARFs for the close sequences.