ARF6 Polyclonal antibody
ARF6 Polyclonal Antibody for IHC,ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human, mouse, rat
Applications
IHC,ELISA
Conjugate
Unconjugated
验证数据展示
产品信息
The immunogen of 18119-1-AP is ARF6 Fusion Protein expressed in E. coli.
Tested Applications | IHC,ELISA |
Tested Reactivity | human, mouse, rat |
Immunogen | ARF6 fusion protein Ag12642 种属同源性预测 |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Full Name | ADP-ribosylation factor 6 |
Synonyms | ADP ribosylation factor 6, ARF6 |
Calculated Molecular Weight | 20 kDa |
GenBank Accession Number | BC002952 |
Gene Symbol | ARF6 |
Gene ID (NCBI) | 382 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
UNIPROT ID | P62330 |
Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
ADP-ribosylation factors (ARFs) are members of the ARF family of GTP-binding proteins of the Ras superfamily, with 20kda protein size. ARFs bind and regulate GTP/GDP cycle by alternating between the active GTP-bound and inactive GDP-bound conformations. ARF family proteins are essential and ubiquitous in eukaryotes. Six highly conserved members of the family have been identified in mammalian cells. They function in vesicular traffic and actin remodelling and other bioprocesses in cells. The ARF6 is one of best identified ARFs It is present at the plasma membrane and to some extent on endosomal membranes where it regulates the flow of trafficking into and out of the cell and the actin cytoskeleton. (PMID: 7759471, PMID: 16042562). This antibody can bind ARFs for the close sequences.