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AKR1C3-IN-4

CAS号

1284180-11-5

分子式

C14H10F3NO2

主要靶点

NADPH

仅限科研使用

Cat No : CM11015

Print datasheet

Synonyms

cancer|castrate|aldo-keto|AKR1C3IN4|AKR-1C3-IN-4|AKR1C3-IN-4|AKR1C3|AKR1C3 IN 4|AKR1C2|1C3|inhibit|CRPC|prostate|resistant|reductase|Inhibitor

验证数据展示

  • CAS No.: 1284180-11-5

    AKR1C3-IN-4
    CAS#: 1284180-11-5

产品信息

CAS号 1284180-11-5
分子式 C14H10F3NO2
主要靶点 NADPH
主要通路 代谢
分子量 281.23
纯度 98.84%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
别名 cancer|castrate|aldo-keto|AKR1C3IN4|AKR-1C3-IN-4|AKR1C3-IN-4|AKR1C3|AKR1C3 IN 4|AKR1C2|1C3|inhibit|CRPC|prostate|resistant|reductase|Inhibitor

靶点活性

AKR1C2:15.1 μM (IC50)|AKR1C3:0.56 μM (IC50)

体外活性

The IC50 of AKR1C3-IN-4 for AKR1C2 is 15.1 μM[1].

溶解度

DMSO:100 mg/mL (355.58 mM)

参考文献

1.Adegoke O Adeniji, et al. Development of potent and selective inhibitors of aldo-keto reductase 1C3 (type 5 17β-hydroxysteroid dehydrogenase) based on N-phenyl-aminobenzoates and their structure-activity relationships. J Med Chem. 2012 Mar 8;55(5):2311-23.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
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C1   V1   C2   V2