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(S)-Malic acid

CAS号

97-67-6

分子式

C4H6O5

主要靶点

Others|Endogenous Metabolite

仅限科研使用

Cat No : CM01876

Print datasheet

Synonyms

Inhibitor|L-(-)-Malic acid|L-苹果酸|Malic acid|L-Malic acid|Endogenous Metabolite|inhibit|HYDROXYSUCCINIC ACID|EndogenousMetabolite|2-Hydroxysuccinic acid|(S)-2-Hydroxysuccinic acid|(S)-(-)-HYDROXYSUCCINIC ACID|(S) Malic acid|(S)Malic acid|(S)-Malic acid|(S)-Hydroxybutanedioic acid|(S)-E 296

验证数据展示

  • CAS No.: 97-67-6

    (S)-Malic acid
    CAS#: 97-67-6

产品信息

CAS号 97-67-6
分子式 C4H6O5
主要靶点 Others|Endogenous Metabolite
主要通路 代谢
分子量 134.09
纯度 99.86%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
别名 Inhibitor|L-(-)-Malic acid|L-苹果酸|Malic acid|L-Malic acid|Endogenous Metabolite|inhibit|HYDROXYSUCCINIC ACID|EndogenousMetabolite|2-Hydroxysuccinic acid|(S)-2-Hydroxysuccinic acid|(S)-(-)-HYDROXYSUCCINIC ACID|(S) Malic acid|(S)Malic acid|(S)-Malic acid|(S)-Hydroxybutanedioic acid|(S)-E 296

体外活性

研究表明，ME对于L. casei中(S)-Malic acid(L-苹果酸)的利用是必要的。此外，如果删除编码组氨酸激酶或TC系统的应答调节器的基因，会导致丧失在(S)-Malic acid上生长的能力，这说明相应的TC系统调控并对ME的表达是必需的。转录分析显示，maeE的表达在(S)-Malic acid存在的情况下被诱导，在葡萄糖存在的情况下被抑制，而TC系统的表达则是由(S)-Malic acid诱导并且不被葡萄糖抑制。

溶解度

DMSO:27.5 mg/mL (205.09 mM)

参考文献

1.Sreekumar A, Poisson L M, Rajendiran T M, et al. Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression.[J]. Nature, 2009, 457(7231):910-914.
2.Landete JM, et al. Requirement of the Lactobacillus casei MaeKR two-component system for L-malic acid utilization via a malic enzyme pathway. Appl Environ Microbiol. 2010 Jan;76(1):84-95.

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The dilution calculator equation

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