|Activity||0.28-1.4 ng/mL EC50|
|Molecular Mass||36 kDa, monomer, glycosylated|
|Formulation||1x PBS, See Certificate of Analysis for details|
Stability and Reconstitution
|Stability and Storage||Lyophilized proteins are stable for 1 year from the date of receipt if stored between (-20°C) and (-80°C). Upon reconstitution we recommend that the solution can be stored at (4°C) for short term or at (-20°C) to (-80°C) for long term. Repeated freeze thaw cycles should be avoided with reconstituted products.|
|Reconstitution||Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile 1xPBS pH 7.4 containing 0.1% endotoxin-free recombinant human serum albumin (HSA).|
Erythropoietin (Epo) is a member of the EPO/TPO family. It is a secreted, glycosylated cytokine composed of four alpha helical bundles. Epo is found in the plasma and regulates erythrocyte production by promoting erythroid differentiation and initiating hemoglobin synthesis through activation of its cognate receptor (PMID 29458727). Epo also has neuroprotective activity against a variety of potential brain injuries and anti-apoptotic functions in several tissue types (PMID 11854521).
EP, EPO, Epoetin, erythropoietin, MVCD2
Ulk1-mediated Atg5-independent macroautophagy mediates elimination of mitochondria from embryonic reticulocytes.
Brief report: efficient generation of hematopoietic precursors and progenitors from human pluripotent stem cell lines.
Artif Cells Nanomed Biotechnol
EPO could be regulated by HIF-1 and promote osteogenesis and accelerate bone repair.
J Labelled Comp Radiopharm
99m Tc-labeled rHuEpo for imaging of the erythropoietin receptor in tumors.