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验证数据展示

  • WB analysis using 14529-1-AP (same clone as 14529-1-PBS)

    WB analysis using 14529-1-AP (same clone as 14529-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 14529-1-AP (ZNF410 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 14529-1-PBS in a different storage buffer formulation.

  • WB analysis using 14529-1-AP (same clone as 14529-1-PBS)

    WB analysis using 14529-1-AP (same clone as 14529-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 14529-1-AP (ZNF410 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 14529-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO验证

ZNF410 Polyclonal antibody, PBS Only

ZNF410 Polyclonal Antibody for WB, Indirect ELISA
Cat No. 14529-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, Indirect ELISA

别名

Zinc finger protein APA 1, Zinc finger protein 410, APA1, APA 1, Another partner for ARF 1

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

14529-1-PBS targets ZNF410 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 ZNF410 fusion protein Ag6028 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 zinc finger protein 410
别名 Zinc finger protein APA 1, Zinc finger protein 410, APA1, APA 1, Another partner for ARF 1
计算分子量 52 kDa
观测分子量52-67 kDa
GenBank蛋白编号BC050683
基因名称 ZNF410
Gene ID (NCBI) 57862
RRIDAB_2257520
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ86VK4
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

ZNF410 (Zinc Finger Protein 410) is a transcription factor involved in the regulation of gene expression, particularly in the context of fetal hemoglobin (HbF) repression and chromatin remodeling. This protein is highly conserved among mammals and plays a crucial role in erythroid cells. The study found that ZNF410 uniquely silences HbF by activating its sole target gene, CHD4, a known HbF repressor in erythroid cells. (PMID: 40158221)