验证数据展示
产品信息
22161-1-PBS targets ZNF154 in WB, Indirect ELISA applications and shows reactivity with human, monkey samples.
经测试应用 | WB, Indirect ELISA Application Description |
经测试反应性 | human, monkey |
免疫原 | ZNF154 fusion protein Ag17812 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Polyclonal |
产品类型 | Antibody |
全称 | zinc finger protein 154 |
别名 | |
计算分子量 | 437 aa, 50 kDa |
观测分子量 | 55-60 kDa |
GenBank蛋白编号 | BC152404 |
基因名称 | ZNF154 |
Gene ID (NCBI) | 7710 |
RRID | AB_2879012 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Antigen affinity purification |
UNIPROT ID | Q13106 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Sites that display recurrent, aberrant DNA methylation in cancer represent potential biomarkers for screening and diagnostics. Previously, The hypermethylation at the ZNF154 CpG island in 15 solid epithelial tumor types from 13 different organs. The magnitude and reproducibility of the ZNF154 hypermethylation signal across five solid tumor types reinforces the potential of this site as a biomarker for circulating tumor DNA (ctDNA)(PMID: 26857064 ). The calculated molecular weight of ZNF154 is 50 kDa, but the modified ZNF154 protein is about 55-60 kDa.