验证数据展示
产品信息
13327-1-PBS targets VPS54 in WB, IP, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
经测试应用 | WB, IP, Indirect ELISA Application Description |
经测试反应性 | human, mouse, rat |
免疫原 | VPS54 fusion protein Ag4123 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Polyclonal |
产品类型 | Antibody |
全称 | vacuolar protein sorting 54 homolog (S. cerevisiae) |
别名 | Vacuolar protein sorting-associated protein 54, Tumor antigen SLP-8p, Tumor antigen HOM-HCC-8, Hepatocellular carcinoma protein 8, HCC8 |
计算分子量 | 977 aa, 111 kDa |
观测分子量 | 111 kDa |
GenBank蛋白编号 | BC030275 |
基因名称 | VPS54 |
Gene ID (NCBI) | 51542 |
RRID | AB_2304414 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Antigen affinity purification |
UNIPROT ID | Q9P1Q0 |
储存缓冲液 | PBS only, pH 7.3. |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
VPS54 is a part of the Golgi-associated retrograde protein (GARP) complex protein required for tethering and fusion of endosome-derived transport vesicles to the trans-Golgi network. It may particpate in retrograde transport from early and late endosomes to the late Golgi. The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD.