TNC/Tenascin-C Recombinant antibody, PBS Only

TNC/Tenascin-C Uni-rAbTM Recombinant Antibody for WB, IHC, Cytometric bead array, Indirect ELISA
Cat No. 83767-1-PBS

产品说明书

CloneNo. 240844A2

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, IHC, Cytometric bead array, Indirect ELISA

Tenascin, TNC, 240844A2, Glioma-associated-extracellular matrix antigen, GMEM

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存


Planning an IHC experiment? We recommend our IHCeasy TNC/Tenascin-C Ready-To-Use IHC Kit. TNC/Tenascin-C primary antibody included.

产品信息

83767-1-PBS targets TNC/Tenascin-C in WB, IHC, Cytometric bead array, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IHC, Cytometric bead array, Indirect ELISA Application Description
经测试反应性 human
免疫原 TNC/Tenascin-C fusion protein Ag27122 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 tenascin C
别名 Tenascin, TNC, 240844A2, Glioma-associated-extracellular matrix antigen, GMEM
计算分子量 2201 aa, 241 kDa
观测分子量220-350 kDa, 190-240 kDa
GenBank蛋白编号BC151843
基因名称 Tenascin C
Gene ID (NCBI) 3371
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP24821
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Tenascin-C (TNC) is a large hexameric extracellular matrix glycoprotein of the tenascin family (PMID: 21818551). It is a multimodular protein containing multiple epidermal growth factor (EGF)-like repeats and fibronectin type III (FN III) domains (PMID: 1719530). Tenascin-C is highly expressed during embryonic development, particularly in the developing central nervous system, around motile cells and at epithelial-mesenchymal interaction sites (PMID: 25738825). In adult tissues, the expression and the distribution of TNC are typically limited under normal physiological conditions. It is upregulated during injury, inflammation, regeneration, and cancer (PMID: 7694605; 25120494). Tenascin-C is a diverse protein that can produce different functions including regulating cell adhesion, migration and proliferation.

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