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Species Reactivity
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Conjugate
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验证数据展示

  • IHC staining of mouse brain using 28031-1-AP (same clone as 28031-1-PBS)

    IHC staining of mouse brain using 28031-1-AP (same clone as 28031-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 28031-1-AP (TMEM184B antibody) at dilution of 1:500 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 28031-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse brain using 28031-1-AP (same clone as 28031-1-PBS)

    IHC staining of mouse brain using 28031-1-AP (same clone as 28031-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 28031-1-AP (TMEM184B antibody) at dilution of 1:500 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 28031-1-PBS in a different storage buffer formulation.

TMEM184B Polyclonal antibody, PBS Only

TMEM184B Polyclonal Antibody for IHC, Indirect ELISA
Cat No. 28031-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

IHC, Indirect ELISA

别名

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

28031-1-PBS targets TMEM184B in IHC, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 IHC, Indirect ELISA Application Description
经测试反应性 human
免疫原 TMEM184B fusion protein Ag27704 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 transmembrane protein 184B
别名
GenBank蛋白编号BC015489
基因名称 TMEM184B
Gene ID (NCBI) 25829
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9Y519
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Transmembrane protein 184B (TMEM184B) is a seven-pass transmembrane protein highly expressed in the nervous system and is thought to play a role in neuronal excitability, synaptic structure, and expression of key developmental and adult pathways involved in neuronal differentiation (PMID: 27122027; 37730546). TMEM184B may activate the MAP kinase signaling pathway (PMID: 12761501). TMEM184B has also been reported to be necessary for interleukin-31-induced itch, promoting adult somatosensation through developmental Wnt signaling and promotion of proper pruriceptive gene expression (PMID: 34629389).