验证数据展示
经过测试的应用
| Positive WB detected in | HeLa cells |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:500-1:2000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
发表文章中的应用
| KD/KO | See 1 publications below |
| WB | See 2 publications below |
产品信息
13579-1-AP targets STK24 in WB, ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, ELISA Application Description |
| 文献引用应用 | WB |
| 经测试反应性 | human |
| 文献引用反应性 | human, rat |
| 免疫原 | STK24 fusion protein Ag4483 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | serine/threonine kinase 24 (STE20 homolog, yeast) |
| 别名 | EC:2.7.11.1, Mammalian STE20-like protein kinase 3, MST3, Serine/threonine-protein kinase 24 12 kDa subunit, Serine/threonine-protein kinase 24 36 kDa subunit |
| 计算分子量 | 431 aa, 48 kDa |
| 观测分子量 | 50 kDa |
| GenBank蛋白编号 | BC035578 |
| 基因名称 | STK24 |
| Gene ID (NCBI) | 8428 |
| RRID | AB_2198769 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q9Y6E0 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Serine/threonine-protein kinase 24 (STK24), also named MST3, belonging to GCK subfamily of STE20-like kinases, acts on both serine and threonine residues and promotes apoptosis in response to stress stimuli and caspase activation (PMID:12107159, 10644707). STK24 and STK25 operate in the same cardiovascular development pathway with programmed cell death 10 (CCM3) (PMID: 20332113). It regulates axon outgrowth in forebrain neurons (PMID: 17114295).
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for STK24 antibody 13579-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
发表文章
| Species | Application | Title |
|---|---|---|
Biomed Pharmacother Hydrogen sulfide ameliorated preeclampsia via suppression of toll-like receptor 4-activated inflammation in the rostral ventrolateral medulla of rats. | ||
Mediators Inflamm STK24 Promotes Progression of LUAD and Modulates the Immune Microenvironment
| ||
Phytother Res 7-Hydroxyflavone improves nonalcoholic fatty liver disease by acting on STK24 |