验证数据展示
产品信息
13315-1-PBS targets SLD5 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse samples.
经测试应用 | WB, IF/ICC, Indirect ELISA Application Description |
经测试反应性 | human, mouse |
免疫原 | SLD5 fusion protein Ag4158 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Polyclonal |
产品类型 | Antibody |
全称 | GINS complex subunit 4 (Sld5 homolog) |
别名 | GINS4, GINS complex subunit 4, DNA replication complex GINS protein SLD5, N-terminally processed |
计算分子量 | 223 aa, 26 kDa |
观测分子量 | 26 kDa |
GenBank蛋白编号 | BC027454 |
基因名称 | SLD5 |
Gene ID (NCBI) | 84296 |
RRID | AB_2109671 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Antigen affinity purification |
UNIPROT ID | Q9BRT9 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
SLD5 (DNA replication complex GINS protein SLD5) is also named as GINS4 (GINS complex subunit 4). SLD5 is required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks (PMID: 17417653). SLD5 forms a GINS complex with PSF1, PSF2 and PSF3, which is essential for the initiation of DNA replication in lower eukaryotes (PMID: 24244394). SLD5 is a member of the GINS complex, essential for DNA replication in eukaryotes. It has been reported that SLD5 is involved in early embryogenesis in the mouse, and cell cycle progression and genome integrity in Drosophila (PMID: 27499248).