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验证数据展示

  • WB analysis using 30232-1-AP (same clone as 30232-1-PBS)

    WB analysis using 30232-1-AP (same clone as 30232-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 30232-1-AP (SLC7A2 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 30232-1-PBS in a different storage buffer formulation.

  • IHC staining of human stomach cancer using 30232-1-AP (same clone as 30232-1-PBS)

    IHC staining of human stomach cancer using 30232-1-AP (same clone as 30232-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human stomach cancer tissue slide using 30232-1-AP (SLC7A2 antibody) at dilution of 1:160 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 30232-1-PBS in a different storage buffer formulation.

SLC7A2 Polyclonal antibody, PBS Only

SLC7A2 Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 30232-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, Indirect ELISA

别名

HCAT2, Cationic amino acid transporter 2, CAT-2

缓冲液配方:  PBS Only
PBS, Azide, Glycerol
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

30232-1-PBS targets SLC7A2 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原

CatNo: Ag31207

Product name: Recombinant human SLC7A2 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 568-657 aa of BC104905

Sequence: ILVNIYLMVQLSADTWVRFSIWMAIGFLIYFSYGIRHSLEGHLRDENNEEDAYPDNVHAAAEEKSAIQANDHHPRNLSSPFIFHEKTSEF

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
别名 HCAT2, Cationic amino acid transporter 2, CAT-2
计算分子量 698 aa, 76 kDa
观测分子量 76 kDa
GenBank蛋白编号BC104905
基因名称 SLC7A2
Gene ID (NCBI) 6542
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDP52569
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Solute carrier family 7 member 2 (SLC7A2), also known as CAT2, is a member of the solute carrier superfamily. It functions as a cationic amino acid transporter, which can transport cationic amino acids (arginine, lysine and ornithine) into the cytosol and regulate inflammation (PMID: 35152203). It has been shown that lower SLC7A2 expression is associated with worse prognosis of ovarian cancer and hepatocellular carcinoma (PMID: 34108444; 32647070), and SLC7A2 deficiency in inflammatory bowel tissues increases the risk of inflammation-associated colon tumorigenesis (PMID: 30202097)

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