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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 30232-1-AP (same clone as 30232-1-PBS)

    WB analysis using 30232-1-AP (same clone as 30232-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 30232-1-AP (SLC7A2 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 30232-1-PBS in a different storage buffer formulation.

  • IHC staining of human stomach cancer using 30232-1-AP (same clone as 30232-1-PBS)

    IHC staining of human stomach cancer using 30232-1-AP (same clone as 30232-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human stomach cancer tissue slide using 30232-1-AP (SLC7A2 antibody) at dilution of 1:160 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 30232-1-PBS in a different storage buffer formulation.

SLC7A2 Polyclonal antibody, PBS Only

SLC7A2 Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 30232-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, Indirect ELISA

别名

HCAT2, Cationic amino acid transporter 2, CAT-2

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

30232-1-PBS targets SLC7A2 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 SLC7A2 fusion protein Ag31207 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
别名 HCAT2, Cationic amino acid transporter 2, CAT-2
计算分子量 698 aa, 76 kDa
观测分子量 76 kDa
GenBank蛋白编号BC104905
基因名称 SLC7A2
Gene ID (NCBI) 6542
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDP52569
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Solute carrier family 7 member 2 (SLC7A2), also known as CAT2, is a member of the solute carrier superfamily. It functions as a cationic amino acid transporter, which can transport cationic amino acids (arginine, lysine and ornithine) into the cytosol and regulate inflammation (PMID: 35152203). It has been shown that lower SLC7A2 expression is associated with worse prognosis of ovarian cancer and hepatocellular carcinoma (PMID: 34108444; 32647070), and SLC7A2 deficiency in inflammatory bowel tissues increases the risk of inflammation-associated colon tumorigenesis (PMID: 30202097)