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Species Reactivity
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Species Reactivity
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Conjugate
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Conjugate
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Compatible Species
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验证数据展示

  • WB analysis using 32593-1-AP

    WB analysis using 32593-1-AP

    Various lysates were subjected to SDS PAGE followed by western blot with 32593-1-AP (SEC14L2 antibody) at dilution of 1:6000 incubated at room temperature for 1.5 hours.

SEC14L2 Polyclonal antibody

SEC14L2 Polyclonal Antibody for WB, ELISA
Cat No. 32593-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, ELISA

别名

Alpha-tocopherol-associated protein, C22orf6, hTAP, KIAA1186, KIAA1658

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
Unconjugated
规格价格库存

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经过测试的应用

Positive WB detected inHEK-293T cells, RKO cells, fetal human brain tissue, mouse brain tissue, mouse liver tissue

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:2000-1:12000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

32593-1-AP targets SEC14L2 in WB, ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, ELISA Application Description
经测试反应性 human, mouse
免疫原 SEC14L2 fusion protein Ag35592 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 SEC14-like 2 (S. cerevisiae)
别名 Alpha-tocopherol-associated protein, C22orf6, hTAP, KIAA1186, KIAA1658
计算分子量 46 kDa
观测分子量44 kDa
GenBank蛋白编号BC058915
基因名称 SEC14L2
Gene ID (NCBI) 23541
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity Purification
UNIPROT IDO76054
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

SEC14L2 (SEC14-like lipid-binding protein 2) is a cytoplasmic protein that belongs to the lipid-binding protein family. It plays an important role in a variety of cellular processes, including endosome division and lipid metabolism. SEC14L2 is able to bind phosphatidylinositol (PtdIns) and regulate its intracellular distribution, which is essential for normal endosome division. It has been shown that SEC14L2 regulates the endosome division process by promoting the conversion of PtdIns4P to PtdIns3P. In addition, SEC14L2 plays a role in the cholesterol biosynthesis pathway by stimulating squalene monooxygenase activity. In terms of viral infection, SEC14L2 is essential for hepatitis C virus (HCV) replication, and its expression promotes HCV replication in cells.

实验方案

Product Specific Protocols
WB protocol for SEC14L2 antibody 32593-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols