验证数据展示
产品信息
31177-1-PBS targets RBM20 in IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
经测试应用 | IHC, Indirect ELISA Application Description |
经测试反应性 | human, mouse, rat |
免疫原 | RBM20 fusion protein Ag34322 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Polyclonal |
产品类型 | Antibody |
全称 | RNA binding motif protein 20 |
别名 | |
计算分子量 | 134 kDa |
GenBank蛋白编号 | NM_001134363 |
基因名称 | RBM20 |
Gene ID (NCBI) | 282996 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Antigen affinity Purification |
UNIPROT ID | Q5T481 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
RBM20 (RNA binding motif protein 20) is a striated muscle-specific splicing factor that regulates alternative splicing of many cardiac genes encoding sarcomere and calcium-regulatory proteins (PMID: 36417486). RBM20 has been identified as a crucial RNA-binding protein that controls the splicing of TTN (PMID: 30547036). RBM20 is expressed in all striated muscles but is highest in cardiac tissue (PMID: 34575212).