- Featured Product
- KD/KO Validated
Rab23 Monoclonal antibody
Rab23 Monoclonal Antibody for WB,ELISA
Host / Isotype
Mouse / IgG1
Reactivity
human, mouse
Applications
WB,ELISA
Conjugate
Unconjugated
CloneNo.
3E12B6
验证数据展示
经过测试的应用
| Positive WB detected in | human brain tissue, HeLa cells |
推荐稀释比
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:500-1:2000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
发表文章中的应用
| KD/KO | See 1 publications below |
| WB | See 1 publications below |
产品信息
60056-1-Ig targets Rab23 in WB, ELISA applications and shows reactivity with human, mouse samples.
| Tested Applications | WB,ELISA |
| Cited Applications | WB |
| Tested Reactivity | human, mouse |
| Cited Reactivity | human, mouse |
| Immunogen | Rab23 fusion protein Ag1588 种属同源性预测 |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Full Name | RAB23, member RAS oncogene family |
| Synonyms | |
| Calculated Molecular Weight | 237 aa, 27 kDa |
| Observed Molecular Weight | 27-30 kDa |
| GenBank Accession Number | BC015021 |
| Gene Symbol | RAB23 |
| Gene ID (NCBI) | 51715 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | Q9ULC3 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Rab23 is a novel member of large Rab small GTPase family. It plays important roles during embryonic development. The brain-enriched Rab23 is the only Rab protein that is known to have a distinct function during central nervous system development, playing an essential role as a negative regulator of the Sonic Hedgehog (Shh) pathway. RAB23 has recently been identified in mesangial cells (MCs), and could serve as a biomarker that indicates the severity of FSGS ( focal segmental glomerulosclerosis). Mutations in RAB23 may result in ACPS2 ( acrocephalopolysyndactyly type 2).
发表文章
| Species | Application | Title |
|---|---|---|
Curr Biol Planar Cell Polarity Effector Proteins Inturned and Fuzzy Form a Rab23 GEF Complex.
|
